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1-ECBC

Chemical Structure : 1-ECBC

CAS No.: 72755-19-2

1-ECBC

Catalog No.: PC-73393Not For Human Use, Lab Use Only.

1-ECBC is a small molecule inhibiting C. albicans filamentation, 1-ABC targets DYRK1-family kinase Yak1, the sole DYRK-family member expressed in C. albicans.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

1-ECBC is a small molecule inhibiting C. albicans filamentation, 1-ABC targets DYRK1-family kinase Yak1, the sole DYRK-family member expressed in C. albicans.
1-ECBC blocked C. albicans biofilm formation in several co-culture models and a rat catheter infection model.

Physicochemical Properties

M.Wt 240.262
Formula C14H12N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

References

1. MacAlpine J, et al. Nat Commun. 2021 Oct 22;12(1):6151.

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