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Chemical Structure : AZD-0156
CAS No.: 1821428-35-6
Catalog No.: PC-42030Not For Human Use, Lab Use Only.
AZD-0156 (AZD0156, AZD 0156) is a potent, highly selective and orally bioavailable ATM kinase inhibitor with IC50 of 0.58 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $78 | In stock | |
| 10 mg | $118 | In stock | |
| 25 mg | $178 | In stock | |
| 50 mg | $298 | In stock | |
| 100 mg | $488 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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AZD-0156 (AZD0156, AZD 0156) is a potent, highly selective and orally bioavailable ATM kinase inhibitor with IC50 of 0.58 nM.
AZD-0156 exhibits antitumoral activity, both reducing tumor burden and preventing tumors from growing in an immunocompetent allograft mouse model of AML.
| M.Wt | 461.556 | |
| Formula | C26H31N5O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: 6.2 mg/mL (Need ultrasonic and warming) |
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| Chemical Name/SMILES |
2H-Imidazo[4,5-c]quinolin-2-one, 8-[6-[3-(dimethylamino)propoxy]-3-pyridinyl]-1,3-dihydro-3-methyl-1-(tetrahydro-2H-pyran-4-yl)- |
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1. Degorce SL, et al. J Med Chem. 2016 Jul 14;59(13):6281-92.
2. Morgado-Palacin I, et al. Sci Signal. 2016 Sep 13;9(445):ra91.
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