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Chemical Structure : BMS-795311
Catalog No.: PC-63563Not For Human Use, Lab Use Only.
BMS-795311 is a potent and orally available CETP inhibitor with IC50 of 3.8 nM, inhibits cholesteryl ester (CE) transfer with IC50 of 0.22 uM.
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BMS-795311 is a potent and orally available CETP inhibitor with IC50 of 3.8 nM, inhibits cholesteryl ester (CE) transfer with IC50 of 0.22 uM.
BMS-795311 inhibits CE transfer activity at an oral dose of 1 mg/kg in human CETP/apoB-100 dual transgenic mice and increased HDL cholesterol content and size comparable to Torcetrapib in moderately-fat fed hamsters.
| M.Wt | 671.535 | |
| Formula | C33H23F10NO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Qiao JX, et al. J Med Chem. 2015 Nov 25;58(22):9010-26.
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