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CB-6673567

Chemical Structure : CB-6673567

CAS No.: 379218-90-3

CB-6673567 (CB6673567)

Catalog No.: PC-62711Not For Human Use, Lab Use Only.

CB-6673567 is a potent, selective Adenylyl Cyclase 1 (AC1) inhibitor with IC50 of 77 uM, displays a 2- to 4-fold isoform selectivity over AC6.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CB-6673567 is a potent, selective Adenylyl Cyclase 1 (AC1) inhibitor with IC50 of 77 uM, displays a 2- to 4-fold isoform selectivity over AC6; blocks the choline-induced cAMP increase in hippocampal neurons.

Physicochemical Properties

M.Wt 346.346
Formula C19H14N4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1,3-Benzodioxol-4-ol, 5-(1'-phenyl[4,4'-bi-1H-pyrazol]-3-yl)-

References

1. Brand CS, et al. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75.

2. Cheng Q, et al. Neuropharmacology. 2015 Aug;95:405-14.

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