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Chemical Structure : CHMFL-BMX-078
CAS No.: 1808288-51-8
Catalog No.: PC-35179Not For Human Use, Lab Use Only.
CHMFL-BMX-078 is a highly selective, potent, type II irreversible BMX kinase inhibitor with IC50 of 11 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $420 | In stock | |
| 25 mg | $980 | In stock | |
| 100 mg | Get quote | ||
| 500 mg | Get quote |
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CHMFL-BMX-078 is a highly selective, potent, type II irreversible BMX kinase inhibitor with IC50 of 11 nM; displays a high selectivity profile (S score(1) = 0.01) against the 468 kinases/mutants in the KINOMEscan evaluation and achieved at least 40-fold selectivity over BTK kinase; CHMFL-BMX-078 is a useful pharmacological tool to elucidate the detailed mechanism of BMX mediated signaling pathways.
| M.Wt | 625.686 | |
| Formula | C33H35N7O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-((3-Acrylamido-4-methylphenyl)amino)-N-(2-methyl-5-(3,4,5-trimethoxybenzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide |
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1. Liang X, et al. J Med Chem. 2017 Mar 9;60(5):1793-1816.
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