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Chemical Structure : Elexacaftor
CAS No.: 2216712-66-0
Catalog No.: PC-73172Not For Human Use, Lab Use Only.
Elexacaftor (VX-445) is a next-generation cystic fibrosis transmembrane conductance regulator (CFTR) corrector and modulator for cystic fibrosis treatment.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 2 mg | $158 | In stock | |
| 5 mg | $288 | In stock | |
| 10 mg | $458 | In stock | |
| 25 mg | $758 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Elexacaftor (VX-445) is a next-generation cystic fibrosis transmembrane conductance regulator (CFTR) corrector and modulator for cystic fibrosis treatment.
| M.Wt | 597.658 | |
| Formula | C26H34F3N7O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(S)-N-((1,3-Dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)-2-(2,2,4-trimethylpyrrolidin-1-yl)nicotinamide |
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1. Keating D, et al. N Engl J Med. 2018 Oct 25;379(17):1612-1620.
2. Taylor-Cousar JL, et al. ERJ Open Res. 2019 Jun 17;5(2):00082-2019.
3. Middleton PG, et al. N Engl J Med. 2019 Nov 7;381(19):1809-1819.
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