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Chemical Structure : Fasentin
CAS No.: 392721-37-8
Catalog No.: PC-62895Not For Human Use, Lab Use Only.
Fasentin is a novel inhibitor of glucose uptake (GLUT) that sensitizes cancer cells to FAS-induced cell death, preferentially inhibits GLUT4 (IC50=68 uM) over GLUT1.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $78 | In stock | |
| 25 mg | $128 | In stock | |
| 50 mg | $198 | In stock | |
| 100 mg | Get quote |
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Fasentin is a novel inhibitor of glucose uptake (GLUT) that sensitizes cancer cells to FAS-induced cell death, preferentially inhibits GLUT4 (IC50=68 uM) over GLUT1.
Fasentin sensitizes cancer cells to the death ligands FAS and TNF apoptosis-inducing ligand, and induces G1 cell cycle arrest.
| M.Wt | 279.643 | |
| Formula | C11H9ClF3NO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-[4-Chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide |
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1. Wood TE, et al. Mol Cancer Ther. 2008 Nov;7(11):3546-55.
2. Schimmer AD, et al. Cancer Res. 2006 Feb 15;66(4):2367-75.
3. Granchi C, et al. Medchemcomm. 2016 Sep 1;7(9):1716-1729.
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