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Fidarestat

Chemical Structure : Fidarestat

CAS No.: 136087-85-9

Fidarestat (SNK-860;SNK860)

Catalog No.: PC-61992Not For Human Use, Lab Use Only.

Fidarestat (SNK860) is a potent aldose reductase inhibitor, improves motor nerve conduction velocity (MNCV) and metabolic abnormalities in sciatic nerve were investigated in acute STZ-induced diabetic rats..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Fidarestat (SNK860) is a potent aldose reductase inhibitor, improves motor nerve conduction velocity (MNCV) and metabolic abnormalities in sciatic nerve were investigated in acute STZ-induced diabetic rats.

Diabetes

Phase 3 Discontinued

Physicochemical Properties

M.Wt 279.227
Formula C12H10FN3O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S,4S)-6-fluoro-2',5'-dioxospiro[2,3-dihydrochromene-4,4'-imidazolidine]-2-carboxamide

References

1. Mizuno K, et al.

2. Hotta N, et al. Exp Physiol. 1995 Nov;80(6):981-9.

3. Kawamura T, et al. Diabet Med. 1995 May;12(5):392-6.

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