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Filovirus inhibitor compd-A

Chemical Structure : Filovirus inhibitor compd-A

CAS No.: 667432-48-6

Filovirus inhibitor compd-A

Catalog No.: PC-38559Not For Human Use, Lab Use Only.

Filovirus inhibitor compd-A is a small molecule filovirus entry inhibitor targeting the endosomal receptor NPC1 binding site, shows potent inhibitory activity against both Ebola and Marburg viruses with IC50 of 0.86 uM against pseudotyped Marburg virus entry.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Filovirus inhibitor compd-A is a small molecule filovirus entry inhibitor targeting the endosomal receptor NPC1 binding site, shows potent inhibitory activity against both Ebola and Marburg viruses with IC50 of 0.86 uM against pseudotyped Marburg virus entry.

Physicochemical Properties

M.Wt 398.458
Formula C26H22O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

7-(2-(3,4-dimethylphenyl)-2-oxo-1-phenylethoxy)-4-methyl-2H-chromen-2-one

References

1. Leah Liu Wang, et al. Antiviral Res. 2021 May;189:105059.

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