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HG-7-92-01

Chemical Structure : HG-7-92-01

CAS No.: 1315355-93-1

HG-7-92-01 (NG 25)

Catalog No.: PC-61640Not For Human Use, Lab Use Only.

HG-7-92-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 292 nM, displays intermediate selectivity profiles (selectivity score=0.18) against 353 kinases.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

HG-7-92-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 292 nM, displays intermediate selectivity profiles (selectivity score=0.18) against 353 kinases.

Physicochemical Properties

M.Wt 537.587
Formula C29H30F3N5O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO (5.4 mg/mL)

Chemical Name/SMILES

3-((1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methylbenzamide

References

1. Hellwig S, et al. Chem Biol. 2012 Apr 20;19(4):529-40.

2. Weir MC, et al. PLoS One. 2017 Jul 20;12(7):e0181178.

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