Chemical Structure : ITE
CAS No.: 448906-42-1
Catalog No.: PC-45600Not For Human Use, Lab Use Only.
A endogenous ligand, potent aryl hydrocarbon receptor (AhR) agonist in vitro.
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A endogenous ligand, potent aryl hydrocarbon receptor (AhR) agonist in vitro; activates the murine AhR in vivo, but does not induce toxicity; induces the differentiation of stem-like cancer cells and reduces their tumorigenic potential in both subcutaneous and orthotopic xenograft tumour models.
M.Wt | 286.3058 | |
Formula | C14H10N2O3S | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 41 mg/mL |
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Chemical Name/SMILES |
4-Thiazolecarboxylic acid, 2-(1H-indol-3-ylcarbonyl)-, methyl ester |
1. Henry EC, et al. Toxicol Sci. 2010 Mar;114(1):90-100.
2. Wang K, et al. Cancer Lett. 2013 Oct 28;340(1):63-71.
3. Cheng J, et al. Nat Commun. 2015 Jun 10;6:7209.
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