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Chemical Structure : KH7
Catalog No.: PC-60892Not For Human Use, Lab Use Only.
A potent, specific soluble adenylyl cyclase (sAC) inhibitor that inhibits Mn2+-dependent sAC with IC50 of 2.7 uM.
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A potent, specific soluble adenylyl cyclase (sAC) inhibitor that inhibits Mn2+-dependent sAC with IC50 of 2.7 uM; inhibits physiologically stimulated sAC with similar potency with IC50 of 8.0 uM, completely blocks the capacitation-induced rise in cAMP in wild-type sperm at 10 uM, inhibits in vitro fertilization.
| M.Wt | 419.297 | |
| Formula | C17H15BrN4O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Bitterman JL, et al. J Pharmacol Exp Ther. 2013 Dec;347(3):589-98.
2. Hess KC, et al. Dev Cell. 2005 Aug;9(2):249-59.
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