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Chemical Structure : Lexibulin
CAS No.:
Catalog No.: PC-42619Not For Human Use, Lab Use Only.
An orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $136 | In stock | |
| 50 mg | $488 | In stock | |
| 250 mg | Get quote |
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An orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo; inhibits a broad selection of cancer cell lines with IC50 of <100 nM; blocks the cell cycle at the G2-M boundary and increases phosphorylated Bcl-2, expression of cyclin B1; orally bioavailable, and efficacious in a range of in vivo cancer models.
Blood Cancer
Phase 2 Discontinued
| M.Wt | 434.534 | |
| Formula | C24H30N6O2 | |
| Appearance | Solid | |
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| Solubility |
10 mM in DMSO |
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