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Chemical Structure : MDL100907
CAS No.: 139290-65-6
Catalog No.: PC-60814Not For Human Use, Lab Use Only.
MDL100907 (Volinanserin) is a potent, selective 5-HT2A receptor antagonist with Ki of 0.36 nM, > 80-fold selectivity for 5-HT2A over other serotonergic receptors.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $198 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | $528 | In stock | |
| 100 mg | Get quote |
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MDL100907 (Volinanserin) is a potent, selective 5-HT2A receptor antagonist with Ki of 0.36 nM, > 80-fold selectivity for 5-HT2A over other serotonergic receptors.
MDL100907 demonstrates a clozapine-like profile of potential antipsychotic activity with low extrapyramidal sid-effect liability, and has a superior CNS safety index.
| M.Wt | 373.46 | |
| Formula | C22H28FNO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(R)-(+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperinemethanol |
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1. Ardayfio PA, et al. J Pharmacol Exp Ther. 2008 Dec;327(3):891-7.
2. Sorensen SM, et al. J Pharmacol Exp Ther. 1993 Aug;266(2):684-91.
3. Kehne JH, et al. J Pharmacol Exp Ther. 1996 May;277(2):968-81.
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