Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : ML-9 hydrochloride
Catalog No.: PC-62887Not For Human Use, Lab Use Only.
ML-9 hydrochloride is a potent, ATP-competitive myosin light chain kinase (MLCK) inhibitor with Ki of 3.8 uM, inhibits Store-operated Ca2+ entry (SOCE) in a variety of cell lines.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
ML-9 hydrochloride is a potent, ATP-competitive myosin light chain kinase (MLCK) inhibitor with Ki of 3.8 uM, inhibits Store-operated Ca2+ entry (SOCE) in a variety of cell lines; also inhibits PKA and PKC with Ki of 32 and 54 uM; inhibits STIM1-plasma membrane interactions and inhibits TRPC6 channels via a mechanism independent of inhibition of MLCK activity.
| M.Wt | 361.281 | |
| Formula | C15H18Cl2N2O2S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Shi J, et al. Br J Pharmacol. 2007 Sep;152(1):122-31.
2. Várnai P, et al. Trends Pharmacol Sci. 2009 Mar;30(3):118-28.
3. Ito S, et al. Eur J Pharmacol. 2004 Feb 23;486(3):325-33.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
