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Chemical Structure : Pitstop 1
Catalog No.: PC-60189Not For Human Use, Lab Use Only.
A potent, selective inhibitor of clathrin-independent endocytosis with IC50 of 18 uM (inhibition of clathrin TD-amphiphysin B/C complex formation).
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Pitstop 1 is a potent, selective inhibitor of clathrin-independent endocytosis with IC50 of 18 uM (inhibition of clathrin TD-amphiphysin B/C complex formation).
Pitstop 1 inhibits endocytic recycling of synaptic vesicles in neurons and in situ.
| M.Wt | 404.37 | |
| Formula | C19H13N2NaO5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. von Kleist L, et al. Cell. 2011 Aug 5;146(3):471-84.
2. Nilewski LG, et al. ACS Chem Neurosci. 2017 Aug 14. doi: 10.1021/acschemneuro.7b00138.
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