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Chemical Structure : RN-18
CAS No.: 431980-38-0
Catalog No.: PC-62712Not For Human Use, Lab Use Only.
RN-18 is a small molecule that antagonizes HIV-1 Vif function and inhibits HIV-1 replication only in the presence of A3G.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg (4 weeks) | $288 | In stock | |
| 100 mg (4 weeks) | $478 | In stock | |
| 250 mg (4 weeks) | $728 | In stock | |
| 1 g | Get quote |
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RN-18 is a small molecule that antagonizes HIV-1 Vif function and inhibits HIV-1 replication only in the presence of A3G; increases cellular A3G levels in a Vif-dependent manner and increases A3G incorporation into virions without inhibiting general proteasome-mediated protein degradation; enhances Vif degradation, reduces viral infectivity by increasing A3G incorporation into virions and enhances cytidine deamination of the viral genome.
| M.Wt | 380.418 | |
| Formula | C20H16N2O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-(2-Methoxyphenyl)-2-[(4-nitrophenyl)thio]benzamide |
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1. Nathans R, et al. Nat Biotechnol. 2008 Oct;26(10):1187-92.
2. Mohammed I, et al. J Med Chem. 2016 Aug 25;59(16):7677-82.
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