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Chemical Structure : VL285
CAS No.: 1448188-57-5
Catalog No.: PC-38610Not For Human Use, Lab Use Only.
VL285 is a potent VHL ligand that degrades HaloTag7 fusion proteins, attenuates the ability of HaloPROTAC3 to induce the degradation of GFP-HaloTag7 (IC50=0.34 uM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $198 | In stock | |
| 50 mg | $328 | In stock | |
| 100 mg | $548 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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VL285 is a potent VHL ligand that degrades HaloTag7 fusion proteins, attenuates the ability of HaloPROTAC3 to induce the degradation of GFP-HaloTag7 (IC50=0.34 uM).
| M.Wt | 532.659 | |
| Formula | C29H32N4O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(2S,4R)-4-Hydroxy-1-((S)-3-methyl-2-(1-oxoisoindolin-2-yl)butanoyl)-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
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1. Buckley DL, et al. ACS Chem Biol. 2015 Aug 21;10(8):1831-7.
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