Cat. No. |
Product Name |
Information |
PC-49159 |
AS2674723
5-HT5A antagonist
|
AS2674723 is a potent, selective and brain-penetrating 5-HT5A receptor antagonist with Ki of 0.75, 0.67 and 1.9 nM against human, rat, mouse 5-HT5A receptors, respectively. |
PC-38843 |
Ritanserin
5-HT2 antagonist
|
Ritanserin (R-55667) is a potent, selective and long-acting 5-HT2 receptor antagonist with Ki of 0.39 nM, shows anxiolytic effects. |
PC-38717 |
UCSF678
5-HT5A agonist
|
UCSF678 is a potent, selective arrestin-biased partial agonist of 5-HT5A serotonin receptor with EC50 of 42 nM. |
PC-38596 |
SB 224289 hydrochloride
5-HT1B antagonist
|
SB 224289 hydrochloride is a potent, selective 5-HT1B inverse agonist/antagonist with pKi value of 8.16, displays >75-fold selectivity over all other 5-HT receptors. |
PC-73309 |
Vabicaserin
5-HT2C agonist
|
Vabicaserin (SCA-136) is a potent, selective 5-HT2C receptor full agonist with EC50 of 8 nM, Emax 100%. |
PC-73307 |
Felcisetrag
5-HT4 agonist
|
Felcisetrag (TAK-954, TD-8954) is a highly selective and potent 5-HT4 receptor agonist with pKi of 9.4 (human 5-HT4). |
PC-73306 |
ASP2205
5-HT2C agonist
|
ASP2205 (ASP2205 fumarate) is a potent, selective 5-HT2C receptor agonist with EC50 of 0.85/2.5 nM for human/rat 5-HT2C in the intracellular Ca2+ mobilization assays, respectively. |
PC-73305 |
PZ-1361
5-HT7 antagonist
|
PZ-1361 is a potent and selective 5-HT7 receptor antagonist with Ki of 33 nM, exhibit significant in vivo antidepressant and pro-cognitive properties in rodents. |
PC-73304 |
AGH-192
5-HT7 agonist
|
AGH-192 is a potent, selective, orally bioavailable 5-HT7 receptor agonist with Ki of 4 nM. |
PC-73303 |
AGH-107
5-HT7 agonist
|
AGH-107 is a potent, selective 5-HT7 receptor agonist with Ki of 6 nM and EC50 of 19 nM, 176-fold selectivity over 5-HT1AR. |
PC-73302 |
AVN-492
5-HT6 antagonist
|
AVN-492 is a highly potent and selective 5-HT6 receptor antagonist with Ki of 91 pM, >1000-fold selectivity over 5-HT2BR (Ki=170 nM). |
PC-73301 |
ST1936 oxalate
5-HT6 agonist
|
ST1936 is a potent, selective 5-HT6 receptor agonist with Ki of 13 nM, >10-fold selectivity over 5-HT7 and 5-HT2B receptors. |