Cat. No. |
Product Name |
Information |
PC-61195 |
BRD-7880
|
A potent and highly specific inhibitor of Aurora B and Aurora C with IC50 of 7 and 12 nM respectively, with less activity against Aurora A (IC50>2 uM). |
PC-61110 |
SA 16
|
A potent, dual PDK1 and Aurora kinase A inhibitor with IC50 of 416 and 35 nM, respectively. |
PC-60347 |
AKCI
|
A small-molecule inhibitor that blocks the Aurora C/IκBα interaction (IC50=24.9 uM) and exerts antitumor activity in MDA-MB-231 breast cancer cells. |
PC-42340 |
AZD1152-HQPA
|
The active product of AZD1152, a potent, selective inhibitor of Aurora B kinase with IC50 of 0.37 nM. |
PC-42424 |
MLN8054
|
A potent, selective, ATP-competitive, orally active Aurora A kinase inhibitor with IC50 of 4 nM. |
PC-45943 |
GSK-1070916
|
A potent, selective and ATP-competitive inhibitor of Aurora B and C with Ki of 0.38 nM and 1.5 nM, respectively. |
PC-42612 |
SCH-1473759 hydrochloride
|
A potent, picomolar, dual inhibitor of Aurora A and B with IC50 of 0.02 and 0.03 nM, respectively. |
PC-42611 |
SCH-1473759
|
A potent, picomolar, dual inhibitor of Aurora A and B with IC50 of 0.02 and 0.03 nM, respectively. |
PC-42703 |
CCT 137690
|
A potent, orally bioavailable Aurora kinases inhibitor with IC50 of 15/25/19 nM for Aurora A/B/C. |
PC-42420 |
PHA-680632
|
A potent, highly selective Aurora kinase inhibitor with IC50 of 27, 135 and 120 nM for Aurora A, B and C, respectively. |
PC-45948 |
Aurora A-IN-10
|
A potent, highly selective Aurora A inhibitor with IC50 of 3.4 nM. |
PC-42650 |
CYC-116
|
A potent and selective Aurora A/Aurora B inhibitor with IC50 of 8.0/9.2 nM. |