Cat. No. |
Product Name |
Information |
PC-38364 |
MCB-3681
Bactericidal antibiotic
|
MCB 3681 is a quinolonyl-oxazolidinone bactericidal antibiotic, has activity in vitro against Gram-positive bacteria. MCB3681 has a potent in vitro activity against C. difficile with MIC90 of 0.064 ug/ml. |
PC-38363 |
LFF-571
Bactericidal antibiotic
|
LFF571 is a semisynthetic thiopeptide and bactericidal antibiotic that interferes with bacterial protein synthesis by inhibition of elongation factor EF-Tu, LFF571 is potent in vitro activity against C.difficile strains with MIC90 of 0.25 ug/mL. |
PC-38362 |
MGB-BP-3
Bactericidal antibiotic
|
MGB-BP-3 is a potent bactericidal antibiotic with a completely novel mode of action, selectively binds to the minor grove of microbial DNA, has the potential for Clostridioides difficile infection (CDI). |
PC-38361 |
Ibezapolstat
DNA pol IIIC inhibitor
|
Ibezapolstat (ACX-362E) is a potent, selective, first-in-class DNA polymerase IIIC (DNA pol IIIC) inhibitor with IC50 of 51 nM (B. Subtilis pol IIIC), inhibits C. difficile efficiently (MIC50, 2 ug/mL). |
PC-73349 |
PTC-672
Ng RNR inhibitor
|
PTC-672 (PTC672) is a novel orally active inhibitor that exhibits a narrow spectrum of activity against Neisseria gonorrhoeae (N. gonorrhoeae, Ng) including MDR isolates (MIC, 0.05 to 0.4 ug/mL), directly inhibits class Ia ribonucleotide reductase (RNR). |
PC-73346 |
Xeruborbactam
Beta-lactamase inhibitor
|
Xeruborbactam (QPX7728) is an ultrabroad-spectrum beta-lactamase inhibitor, inhibits class A extended-spectrum beta-lactamases with IC50 of 1-3 nM, carbapenemases such as KPC (IC50, 2.9 nM), class C P99 (IC50, 22 nM). |
PC-73194 |
AX20017
M.tb PknG inhibitor
|
AX20017 is a highly selective inhibitor of Mycobacterium tuberculosis protein kinase G (PknG) with IC50 of 0.39 uM. |
PC-73144 |
Avibactam sodium
Beta-lactamase inhibitor
|
Avibactam sodium (NXL104) is a novel β-lactamase inhibitor with a non-lactam structural scaffold, irreversibly inhibits lactamase from Mycobacterium tuberculosis. |
PC-73118 |
Burkfloxacin
Burkholderia inhibitor
|
Burkfloxacin (BFX) is a fluoroquinolone analog that potently inhibits growth of intracellular Burkholderia. |
PC-72874 |
mCLB073
Rv1625c agonist
|
mCLB073 (mCLB 073) is a more potent, specific, oral small molecule agonist of the Mtb adenylyl cyclase Rv1625c, an optimized analog of the V-59 for in vivo use. |
PC-72860 |
JCP276
Serine hydrolase inhibitor
|
JCP276 is a novel antibiotic and covalent inhibitor that disrupt M. tuberculosis growth by targeting multiple serine hydrolases. |
PC-72815 |
MBL inhibitor 58
MBL inhibitor
|
MBL inhibitor 58 (InCs compound 58) is a potent broad-spectrum metallo-β-lactamase (MBL inhibitor), active against all MBL classes of major clinical relevance |