Cat. No. |
Product Name |
Information |
PC-72797 |
MBX3132
AcrB inhibitor
|
MBX3132 is a small mocule inhibitor of AcrB multidrug efflux pump, fully potentiates the activity of a broad range of antibiotics at 0.1 uM. |
PC-72742 |
Irloxacin
Antibacterial agent
|
Irloxacin (Pirfloxacin) is a fluorinated quinolone derivative, is an antibacterial agent with proved activity against both gram-positive and gram-negative bacteria. |
PC-72571 |
Mtb CoaBC inhibitor 1f
Mtb CoaBC inhibitor
|
Mtb CoaBC inhibitor 1f is a direct small molecule inhibitor of Mtb 4'-phosphopantothenoyl-l-cysteine synthetase (PPCS, CoaB) domain of the bifunctional Mtb CoaBC (IC50=15.6 uM). |
PC-72522 |
ETX0462
Antibiotic
|
ETX0462 (ETX-0462) is a novel antibiotic with broad-spectrum activity for drug-resistant infections, inhibits Pseudomonas aeruginosa PAO1 with MIC of 0.5 mg/mL. |
PC-72489 |
LolCDE inhibitor compound 2A
LolCDE inhibitor
|
LolCDE inhibitor compound 2A is a small molecule inhibitor that inhibits the growth of P. aeruginosa by interfering with the function of the lipoprotein transport components LolCDE complex. |
PC-72426 |
MAC-545496
GraR inhibitor
|
MAC-545496 (MAC545496) is an antivirulence compound that reverses β-lactam resistance in the community-acquired MRSA USA300 strain via inhibition on GraR function (Kd<0.1 nM). |
PC-72420 |
KYT-1
Arg-gingipain inhibitor
|
KYT-1 is a potent, selective inhibitor of P. gingivalis virulence factor Arg-gingipain (Rgp) with Ki 40 nM (RgpA/B). |
PC-72419 |
KYT-36
Lysine-gingipain inhibitor
|
KYT-36 is a potent, selective, and bioavailable inhibitor of P. gingivalis virulence factor gingipain K (Kgp, lysine-gingipain), potently and selectively inhibits Kgp with Ki of 0.27 nM, respectively. |
PC-72418 |
COR588
Lysine-gingipain inhibitor
|
COR588 is a second-generation small-molecule lysine-gingipain (Kgp) inhibitor. |
PC-72417 |
COR388
Lysine-gingipain inhibitor
|
COR388 (Atuzaginstat) is an orally bioavailable, brain penetrant small-molecule that irreversibly inhibits lysine-gingipain (Kgp) with Ki of <0.01 nM. |
PC-72410 |
FIM1033
FimH inhibitor
|
FIM1033 (FIM-1033) is a potent small-molecule inhibitor of FimH with HAI EC90 of 8 nM, with antibiotica activities, significantly attenuated bacterial loads in pyelonephritis in treated mice. |
PC-72404 |
Compound 11726148
Antitubercular
|
Compound 11726148 is a potent, specific antitubercular agent against Mycobacterium tuberculosis (M. tb) with MIC of 0.05 ug/mL, targets cytochrome bc1 complex. |