Cat. No. |
Product Name |
Information |
PC-49008 |
Fleroxacin
Antibiotic
|
Fleroxacin (AM833, Ro23-6240) is a broad-spectrum fluoroquinolone antibiotic, with activity against a variety of Gram-positive and Gram-negative bacteria with MIC90 values of 0.05 to 3.13 ug/mL. |
PC-47040 |
Brilacidin tetrahydrochloride
Antiviral compound
|
Brilacidin (PMX-30063) is a synthetic, non-peptide, defensin-mimetic compound, exhibits broad-spectrum anti-microbial and anti-SARS-CoV-2 activities. |
PC-47012 |
PC190723
FtsZ inhibitor
|
PC190723 is a small molecule inhibitor of FtsZ with potent and selective anti-staphylococcal activity, inhibits FtsZ and prevents cell division. |
PC-47011 |
DS01750413
FtsZ inhibitor
|
DS01750413 is a novel FtsZ inhibitor and new derivative of PC190723 (Cat. PC-47012), inhibits S. aureus FtsZ protein with IC50 of 2 mg/L, has an IC50 of 0.03 mg/L in cell elongation assay of B. subtilis. |
PC-38636 |
HSGN-189
LTA biosynthesis inhibitor
|
HSGN-189 is a potent lipoteichoic acid (LTA) biosynthesis inhibitor, exhibits potent antibacterial activity against both MRSA and VRE strains with MICs of 1 ug/mL. |
PC-38633 |
GSK2556286
M.tb inhibitor
|
GSK2556286 (GSK286) a novel inhibitor of M. tuberculosis extracellularly in the presence of cholesterol and within human macrophages, inhibits growth within human macrophages with IC50 of 70 nM (H37Rv in THP-1 cells). |
PC-73439 |
Quabodepistat
M.tb DprE1 inhibitor
|
Quabodepistat (OPC-167832) is a highly potent antituberculosis agent with MIC of 0.00024 to 0.002 ug/mL against Mycobacterium tuberculosis, targets DprE1 (IC50=258 nM, recombinant DprE1), an essential enzyme for cell wall biosynthesis. |
PC-73350 |
PTC-847
Ng RNR inhibitor
|
PTC-847 (PTC847) is a novel orally active inhibitor that exhibits a narrow spectrum of activity against Neisseria gonorrhoeae (N. gonorrhoeae, Ng) including MDR isolates (MIC, 0.05 to 0.1 ug/mL), directly inhibits class Ia ribonucleotide reductase (RNR). |
PC-73116 |
DNA gyrase inhibitor EN-7
Bacterial DNA gyrase inhibitor
|
DNA gyrase inhibitor EN-7 (EN-7) is a potent bacterial DNA gyrase inhibitor, is active against pathogenic species that are resistant to ciprofloxacin and other clinically important antibiotics. |
PC-73075 |
GC-072
Bacterial Topo inhibitor
|
GC-072 (GC072) is a potent, 4-oxoquinolizine antibiotic with selective inhibitory activity against bacterial topoisomerases (E. coli Topo II/DNA gyrase, IC50=0.18-1.5 uM). |
PC-73074 |
NPG9
SaNSR inhibitor
|
NPG9 (NSR inhibitor NPG9) is a small molecule inhibitor of streptococcus agalactiae nisin resistance protein (NSR) with 58% inhibition at 100 uM (specific growth inhibition assay). |
PC-72981 |
CBR490
Anti-Wolbachia
|
CBR490 (CBR-490) is a potent and selective antiwolbachial activity compound (Anti-Wolbachia wMel In vitro HCI cell-based assay IC50=33 nM, IC90=283 nM). |