Cat. No. |
Product Name |
Information |
PC-45367 |
Fidaxomicin
|
Fidaxomicin(OPT-80; PAR-101) is a new class of narrow spectrum macrocyclic antibiotic drug, selective eradication of pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria. |
PC-42715 |
Delamanid
|
Delamanid (OPC-67683) is a mycolic acid biosynthesis inhibitor found to be free of mutagenicity and to possess highly potent activity against tuberculosis, including MDR-TB. |
PC-45638 |
Ribocil-C
FMN riboswitch inhibitor
|
Ribocil-C is a highly selective inhibitor of the FMN riboswitch that controls expression of de novo riboflavin (Vitamin B2) biosynthesis in Escherichia coli. |
PC-42665 |
Gatifloxacin
Bacterial DNA gyrase inhibitor
|
Gatifloxacin (PD 135432, AM1155) is a fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV. |
PC-42714 |
PA-824
Antibiotic
|
Pretomanid (PA-824) is an anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid. |
PC-22162 |
MLEB-1934
Bacterial DNA gyrase inhibitor
|
MLEB-1934 is a potent bacterial DNA gyrase inhibitor with MIC of 0.25 μg/mL in MRSA, targets the allosteric pocket of the gyrase. |
PC-22142 |
Mupirocin
FTO inhibitor, Antibiotic
|
Mupirocin (BRL-4910A, Pseudomonic acid) is an orally active antibiotic isolated from Pseudomonas fluorescens, also is an inhibitor of m6A demethylase fat mass and obesity-associated protein (FTO), induces CRC ferroptosis and inhibits tumor growth. |
PC-22138 |
G0775
Bacterial SPase LepB inhibitor
|
G0775 is a novel potent, broad-spectrum antibiotic against Gram-negative bacteria (MDR K. pneumoniae CDC 0106, MIC=0.5 ug/mL), inhibits the Gram-negative type I signal peptidase (SPase) LepB with Ki of 0.44 nM, a new antibiotic target. |
PC-22131 |
Irresistin-16
DHFR inhibitor
|
Irresistin-16 (IRS-16) is a potent bacterial dihydrofolate reductase (DHFR) inhibitor for purified E. coli DHFR (FolA), exhibits potent activity against S.aureus MRSA and N. gonorrhoeae with MIC of 1.56 and 0.03 ug/mL, respectively. |
PC-22130 |
Fluorofolin
DHFR inhibitor
|
Fluorofolin is a potent bacterial dihydrofolate reductase (DHFR) inhibitor with IC50 of 2.5 nM for purified E. coli DHFR (FolA), exhibits potent activity against P. aeruginosa PA14 with MIC of 3.1 ug/mL. |
PC-22093 |
X20404
Mtb Pks13 inhibitor
|
X20404 is a small molecule inhibitor of the thioesterase activity of Mtb polyketide synthase 13 (Pks13) with IC50 of 0.4 uM in the Pks13-TE enzyme assay. |
PC-22092 |
EBL-3647
LpxH inhibitor
|
EBL-3647 is a novel LpxH inhibitor with IC50 of 2.2 nM for E. coli LpxH enzyme, shows potent activity targeting lipopolysaccharide synthesis in Gram-negative bacteria (K. pneumoniae ATCC 13883, MIC 0.5 mg/mL). |