Cat. No. |
Product Name |
Information |
PC-20170 |
MRI-1891
CB1R antagonist
|
MRI-1891 (INV-202) is potent, selective, β-Arrestin-2-biased peripheral cannabinoid-1 receptor (CB1R) antagonist with Ki of 0.3 nM (hCB1R), >2000-fold CB1R/CB2R selectivity. |
PC-49218 |
S-777469
CB2 agonist
|
S-777469 (S777469) is a potent, selective, orally available cannabinoid receptor 2 (CB2) receptor agonist with Ki value of 32 nM (hCB2), >100-fold selectivity over CB1. |
PC-47097 |
LY2828360
CB2 agonist
|
LY2828360 is a potent CB2 receptor agonist with similar affinity for human and rat CB2 receptors with Ki of 40.3 nM and 36.7 nM, respectively, shows EC50 of 20.1 nM in [35S]-GTPγS assays. |
PC-73454 |
Vicasinabin
CB2 agonist
|
Vicasinabin (RG7774, RG-7774) is a potent, selective agonist of cannabinoid receptor 2 (CB2) with cAMP EC50 of 1 nM (hCB2), >800-fold selectivity over CB1 receptor. |
PC-73251 |
ZCZ011
CB1 receptor PAM
|
ZCZ011 is a positive allosteric modulator of CB1 receptor, increases specific binding of CB1 receptor orthosteric agonist [3H]CP55,940 to mouse brain membranes with pEC50 of 6.9. |
PC-72731 |
PSNCBAM-1
CB1 antagonist
|
PSNCBAM-1 is an allosteric antagonist of CB1 receptor with IC50 of 22.5 nM in Ca2+ assays, inhibits [3H]CP55,940 binding with EC50 of 167 nM. |
PC-72730 |
RTICBM-189
CB1 NAM
|
RTICBM-189 is a potent, selective, brain-penetrant CB1 negative allosteric modulator (NAM) with pIC50 of 7.54 in Ca2+ assay, 5.29 in GTPγS assay. |
PC-72729 |
RTICBM-229
CB1 NAM
|
RTICBM-229 is a potent, selective, brain-penetrant CB1 negative allosteric modulator (NAM) with IC50 of 169 nM in Ca2+ assay, 40 nM in GTPγS assay. |
PC-72728 |
RTICBM-74
CB1 NAM
|
RTICBM-74 is a potent, selective, brain-penetrant CB1 negative allosteric modulator (NAM) with IC50 of 23 nM in Ca2+ assays. |
PC-35536 |
VCE-004.3
|
VCE-004.3 (VCE004.3) is a novel semi-synthetic cannabidiol derivative behaving as a dual PPARγ/CB2 agonist and CB1 receptor modulator, binds and activates PPARγ (IC50=3.5 uM) and CB2 receptors (pKi=6.69) and antagonizes CB1 receptor (pKi=5.61). |
PC-43210 |
CB1-IN-4
|
DBPR211 (BPRCB1184, CB1-IN-4) is a potent, selective, peripherally restricted cannabinoid-1 (CB1) receptor antagonist with Ki of 0.3 nM, EC50 of 3.0 nM. |
PC-60761 |
AM-2201
Cannabinoid receptor agonist
|
AM-2201 is a synthetic cannabinoid that acts as a potent, nonselective full agonist for the cannabinoid receptor with EC50 of 38 and 58 nM for CB1 and CB2, respectively. |