| Cat. No. |
Product Name |
Information |
| PC-21437 |
JWH133
CB2 agonist
|
JWH133 (JWH-133) is a potent and selective CB2 agonist with Ki of 3.4 nM, 200-fold selective over CB1 receptors, inhibits glioma growth in vivo. |
| PC-20950 |
AEF0117
CB1 inhibitor
|
AEF0117 (AEF-0117) is a potent, signaling-specific inhibitor of the cannabinoid receptor 1 (CB1), inhibits the decrease in cellular respiration induced by THC (1 µM) in HEK293 cells transfected with hCB1 with IC50 of 3 nM. |
| PC-20747 |
LEI-101
CB2R agonist
|
LEI-101 (LEI 101) is a potent, selective, orally available and peripherally restricted cannabinoid CB2 receptor agonist with binding pKi of 7.5 (hCB2R). |
| PC-20746 |
LEI-102
CB2R agonist
|
LEI-102 (LEI 102) is a potent, selective cannabinoid CB2 receptor agonist with binding pKi of 8.0, 1000-fold selectivity over CB1R. |
| PC-20523 |
(±)-Ibipinabant
CB1 antagonist
|
±)-Ibipinabant ((±)-SLV319) is the racemate of SLV319. (±)-Ibipinabant ((±)-SLV319) is a potent and selective cannabinoid-1 (CB-1) receptor antagonist with IC50 of 22 nM. |
| PC-20522 |
Ibipinabant
CB1 antagonist
|
Ibipinabant (SLV319, BMS-646256) is a potent, selective and orally active antagonist of cannabinoid CB1 receptor with Ki of 7.8 nM, >1000-fold selectivity for CB1 over CB2. |
| PC-20521 |
PF-514273
CB1 antagonist
|
PF-514273 (PF 514273) is a potent, selective and orally active antagonist of cannabinoid CB1 receptor with Ki of 1.0 nM, >10000-fold selectivity for CB1 over CB2. |
| PC-20518 |
JD-5006
CB1 antagonist
|
JD-5006 is a potent, selective and peripherally restricted cannabinoid-1 (CB1) receptor blocker with IC50 of 18 nM, does not inhibit CB2 receptor (IC50>5000 nM). |
| PC-20078 |
URB447
CB1R antagonist
|
URB447 (URB-447) is a peripherally restricted CB(1) antagonist/CB(2) agonist with IC50 of 313 nM (rat CB1) and 41 nM (human CB2). |
| PC-20077 |
AM6545
CB1R antagonist
|
AM6545 (AM-6545) is a potent, selective, oral bioavailable and non-brain-penetrant neutral CB1R antagonist with Ki of 3.3 nM, >100-fold selectivity over CB2R. |
| PC-20051 |
MRL-650
CB1R inhibitor
|
MRL-650 (MRL650) is a potent, selective inverse agonist of CB1 cannabinoid receptor with IC50 of <10 nM. |
| PC-73457 |
Zevaquenabant
CB1R/iNOS inhibitor
|
Zevaquenabant ((S)-MRI-1867) is a peripherally restricted, orally bioavailable dual CB1 receptor/iNOS inhibitor. |
