| Cat. No. |
Product Name |
Information |
| PC-49524 |
FL-1607
Fam20C inhibitor
|
FL-1607 is a novel Fam20C inhibitor with potent anti-proliferative effects on TNBC cells, induces apoptosis and inhibits migration in MDA-MB-468 cells. |
| PC-72809 |
SGC-CK2-1
CK2 inhibitor
|
SGC-CK2-1 is a potent, selective, cell active ATP-competitive inhibitor of host protein kinase Casein Kinase 2 (CSNK2/CK2, pIC50=8.3), inhibits the pathogenic β-coronaviruses including SARS-CoV-2 (MHV pIC50=6.9). |
| PC-72647 |
Multikinase inhibitor 108600
Multikinase inhibitor
|
Multikinase inhibitor 108600 (108600) is a novel multi-kinase inhibitor and inhibitor of TNBC growth (GI50=0.12-0.75 uM), inhibits CK2α1/α2, DYRK1A, 1B, and DYRK2 and TNIK (IC50=5-50 nM). |
| PC-72228 |
CK2 inhibitor KN2
CK2 inhibitor
|
CK2 inhibitor KN2 is a potent, highly selective, cell-permeable, bivalent CK2 inhibitor, binds to CK2α- and CK2α′-based CK2 holoenzymes with Ki of 6.1 nM (CK2α2β2) and 4.0 nM (CK2α′2β2). |
| PC-72167 |
CIGB-300
CK2 inhibitor
|
CIGB-300 (P15-Tat) is a cell-permeable cyclic peptide that modulates CK2 (CSNK2) activity by binding to the phosphoacceptor site on CK2 targets, abrogates the CK2 phosphorylation by blocking recombinant substrates in vitro. |
| PC-36054 |
ON108110
|
ON108110 (ON-108110, ON 108110) is a novel multi-kinase inhibitor of protein kinase CK2 (CK2α1/2, IC50=3/2 nM) as well as CDK4/6 (IC50=2-24 nM). |
| PC-36021 |
GO289
CK2 inhibitor
|
GO289 (GO-289, GO 289) is a potent and selective inhibitor of casein kinase 2 (CK2) with IC50 of 7 nM in in vitro kinase assays, shows minor effects on CKIδ and CKIα activity in vitro. |
| PC-35629 |
BTX161
CK1α degrader
|
BTX161 is a thalidomide analog that mediates degradation of CKIα better than lenalidomide in human AML cells and activates DDR and p53, while stabilizing the p53 antagonist MDM2. |
| PC-35628 |
Casein Kinase inhibitor A86
CK1α inhibitor, CDK7/9 inhibitor
|
Casein Kinase inhibitor A86 (CK1α inhibitor A86) is a novel pan-specific CK1 (CSNK1) inhibitor (Kd=1-10 nM, CK1α Kd=9.8 nM) that co-targets the transcriptional kinases CDK7 and CDK9, with hardly inhibition of CDK8, CDK13, CDK11a, CDK11b, and CDK19. |
| PC-35627 |
Casein Kinase inhibitor A51
CK1α inhibitor, CDK7/9 inhibitor
|
Casein Kinase inhibitor A51 (CK1α inhibitor A51) is a novel pan-specific CK1 (CSNK1) inhibitor (Kd=0.5-20 nM, CK1α Kd=5.3 nM) that co-targets the transcriptional kinases CDK7 and CDK9, with hardly inhibition of CDK8, CDK13, CDK11a, CDK11b, and CDK19. |
| PC-35616 |
BMS-699
CK2 inhibitor
|
BMS-699 (BMS699) is a novel potent, selective, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50 of 0.1 nM (CKα). |
| PC-35185 |
CAM4712
CK2α inhibitor
|
CAM4712 (CAM-4712) is a potent and selective CK2alpha (CK2α) inhibitor with IC50 of 7 uM, exhibits cell growth inhibition in HCT116 cell line with IC50 of 10 uM. |
