| Cat. No. |
Product Name |
Information |
| PC-43460 |
PIK-75
|
PIK-75 is a potent, isoform-selective p110α inhibitor with IC50 of 0.3 nM, displays >100-fold selectivity over p110β, p110δ and PI3K C2b. |
| PC-62996 |
IC 86621
|
IC 86621 is a potent DNA-PK inhibitor with IC50 of 135 nM, also inhibits p110β (IC50=135 nM), less potent for p110α/γ/δ (IC50=880-1,400 nM). |
| PC-62995 |
IC 87361
|
IC 87361 is a potent and selective DNA-PK inhibitor with IC50 of 34 nM, shows >50-fold selectivity over p110β. |
| PC-61970 |
SU-11752
|
SU-11752 is a potent, selective inhibitor of DNA-PK, >500-fold selectivity over PI3Kγ, inhibits DNA double-strand break repair in cells and sensitizs ionizing radiation in cancer cells.. |
| PC-70103 |
NU-7163
|
A poten and selective, ATP-competitive DNA-PK inhibitor with IC50 of 0.19 uM, Ki of 24 nM. |
| PC-45615 |
Compound 401
|
A synthetic inhibitor of DNA-PK also inhibits mTOR (IC50=5.3 uM). |
