| Cat. No. |
Product Name |
Information |
| PC-42902 |
Entinostat
class I HDAC inhibitor
|
Entinostat (MS275) is a potent and selective class I HDACs inhibitor with IC50 of 243/453/248 nM for HDAC1/2/3. |
| PC-42671 |
Valproic acid sodium salt
HDAC inhibitor
|
Valproic acid sodium salt is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2. |
| PC-42670 |
Valproic acid
HDAC inhibitor
|
Valproic acid is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2. |
| PC-42421 |
EDO-S101
HDAC inhibitor
|
EDO-S101 (Tinostamustine) is a fusion molecule comprising of the alkylator bendamustine and the HDAC-inhibitor vorinostat. |
| PC-42126 |
HDACi-4b
HDAC inhibitor
|
A benzamide-type HDAC inhibitor with IC50 of 78 uM for changes of FXN mRNA in affected GM15850 cells. |
| PC-22104 |
STR-V-53
HDAC inhibitor
|
STR-V-53 is a novel glycosylated, liver cancer-selective histone deacetylase (HDAC) inhibitor with IC50 of 24.3/60.1/213.43 nM for HDAC1/2/3/6, demonstrates exquisite selective cytotoxicity against human HCC cells. |
| PC-21991 |
DNMT/HDACi 15a
DNMT/HDAC inhibitor
|
DNMT/HDACi 15a is a potent, dual DNMT and HDAC inhibitor with IC50 of 57, 17 nM for HDAC1, HDAC6 respectively. |
| PC-21870 |
SP-2-225
HDAC6 inhibitor
|
SP-2-225 is a potent, selective HDAC6 inhibitor, improves antitumor immune responses and prevent tumor relapse after radiotherapy. |
| PC-21844 |
RBC1HI
HDAC1/2 inhibitor
|
RBC1HI is a novel small molecule HDAC1/HDAC2 inhibitor, attenuates behavioral manifestations of oxycodone withdrawal, especially in mice with neuropathic pain. |
| PC-21650 |
Tefinostat
HDAC inhibitor
|
Tefinostat (CHR-2845) is a monocyte/macrophage targeted pan histone deacetylase (HDAC) inhibitor, which is cleaved into the active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). |
| PC-21608 |
CM-444
HDAC inhibitor
|
CM-444 is a potent histone deacetylase (HDAC) inhibitor with IC50 of 7/51/18/531 nM for HDAC1/2/3/6 respectively, also inhibits DNMT1 with IC50 of 2160 nM. |
| PC-21607 |
CM-1758
HDAC inhibitor
|
CM-1758 is a novel histone deacetylase (HDAC) inhibitor with IC50 of 5 nM and 126 nM for HDAC1 and HDAC6, respectively. |
