| Cat. No. |
Product Name |
Information |
| PC-72342 |
KA2507
HDAC6 inhibitor
|
KA2507 (KA-2507, KA 2507) is a potent and selective inhibitor of HDAC6 with IC50 of 2.5 nM, >300-fold selectivity over other HDACs. |
| PC-72144 |
Splitomicin
Sir2p inhibitor
|
Splitomicin is a selective Sir2p inhibitor, inhibits NAD+-dependent histone deacetylase activity (HDA) of the Sir2 protein wqith IC50 of 60 uM. |
| PC-72098 |
AES-135
HDAC inhibitor
|
AES-135 (AES135) novel HDAC inhibitor, inhibits HDAC3, HDAC6, HDAC11 with IC50 of 654, 190, 636 nM, with low-uM activity against HDAC8 (IC50=1.2 uM). |
| PC-72096 |
FT108
HDAC6 inhibitor
|
FT108 (FT-108) is a potent, selective HDAC6 inhibitor (IC50=26 nM) relative to other HDAC family members (HDAC3 IC50=6.68 uM and HDAC8 IC50=4.07 uM). |
| PC-72095 |
FT234
HDAC11 inhibitor
|
FT234 (FT-234) is a selective HDAC11 inhibitor. |
| PC-72094 |
Elevenostat
HDAC11 inhibitor
|
Elevenostat (JB3-22) is a selective HDAC11 inhibitor with IC50 of 0.235 uM. |
| PC-72093 |
SS-208
HDAC6 inhibitor
|
SS-208 (SS208) is a novel potent, selective inhibitor of histone deacetylase 6 (HDAC6) with IC50 of 12 nM, >100-fold selectivity over HDAC1/4/5/7/8/9/11. |
| PC-72089 |
PTG-0861
HDAC6 inhibitor
|
PTG-0861 (JG-265) is a novel potent, selective HDAC6 inhibitor with IC50 of 5.92 nM, >36-fold selectivity over other HDACs. |
| PC-38119 |
LSH-A54
|
LSH-A54 is a potent, class I selective HDAC inhibitor with IC50 of 26.2 nM (HDAC1) and 59.3 nM (HDAC2). |
| PC-36094 |
CHR-3996
|
CHR-3996 (Nanatinostat, VRx-3996, CHR3996, Tractinostat) is a potent, class I-selective, orally active HDAC inhibitor with IC50 of 3-7 nM for HDAC1/2/3. |
| PC-36081 |
AES-135
|
AES-135 (AES135) is a novel HDAC inhibitor that biochemically inhibits HDACs 3, 6, 8 and 11 with IC50 values of 190-1100 nM. |
| PC-35926 |
CM-675
|
CM-675 (CM675) is a potent, dual PDE5 and classI-HDAC inhibitor with IC50 of 114/673 nM for PDE5A/HDAC1, respectively. |
