| Cat. No. |
Product Name |
Information |
| PC-45250 |
Emtricitabine
NRTI
|
Emtricitabine (BW-1592) is a nucleoside reverse transcriptase inhibitor (NRTI) for the prevention and treatment of HIV infection, also exhibits clinical activity against the hepatitis B virus (HBV). |
| PC-45074 |
Doravirine
NNRTI
|
Doravirine (MK-1439, MK1439) is a novel, highly specific HIV-1 nonnucleoside reverse transcriptase inhibitor (NNRTI) with IC50 of 12, 9.7, and 9.7 nM against WT, K103N, and Y181C reverse transcriptase (RT) mutants, respectively, in a biochemical assay. |
| PC-42661 |
Rilpivirine
NNRTI
|
Rilpivirine (R278474, TMC278) is a highly potent nonnucleoside inhibitor (NNRTI) of HIV-1 reverse trK7912:M7912anscriptase with IC50 of 0.4 nM for WT HIV-1 in cell-based assay. |
| PC-42660 |
Efavirenz
NNRTI
|
Efavirenz (DMP 266, EFV) is a highly potent nonnucleoside inhibitor (NNRTI) of HIV-1 reverse transcriptase with Ki of 2.93 nM for WT HIV-1 RT. |
| PC-45186 |
Atazanavir
HIV-1 protease inhibitor
|
Atazanavir (BMS-232632) is a highly potent HIV-1 protease inhibitor that exhibits potent anti-HIV activity EC50 of 2.6-5.3 nM and EC90 of 9-15 nM in cell culture. |
| PC-42793 |
BMS-538203
|
BMS-538203 is a chemical intermidate of BMS-626529, a HIV-1 attachment inhibitor that targets gp120. |
| PC-21968 |
Bavtavirine
NNRTI
|
Bavtavirine is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) against HIV-1. |
| PC-21806 |
Cabotegravir
HIV-1 integrase inhibitor
|
Cabotegravir (GSK-1265744) is a potent, selective HIV-1 integrase inhibitor with IC50 of 3 nM in biochemical integrase strand transfer assay (INST). |
| PC-21801 |
GS-9770
HIV-1 protease inhibitor
|
GS-9770 is a potent, selective, non-peptidomimetic and orally active HIV protease inhibitor with Ki(app) value of 0.16 nM (recombinant HIV-1 PR). |
| PC-21700 |
Lopinavir
HIV-1 protease inhibitor
|
Lopinavir (ABT-378) is a highly potent inhibitor of HIV-1 protease with Ki of 1.3 to 3.6 pM for wild-type and mutant HIV protease. |
| PC-21699 |
Tipranavir
HIV-1 protease inhibitor
|
Tipranavir (PNU-140690) is a potent, nonpeptidic and orally bioavailable HIV protease inhibitor with Ki vaule of 8 pM, shows an IC90 value of 100 nM in antiviral cell culture. |
| PC-20826 |
TX-1918
HIV-1 capsid inhibitor
|
TX-1918 (TX1918) is a specific inhibitor of HIV-1 capsid assembly taregting the C-terminal domain of HIV-1 capsid (CA CTD) with IC50 of 3.81 uM, inhibits viral replication (EC50=15.16 μM) and inhibits CA assembly in vitro. |
