Cat. No. |
Product Name |
Information |
PC-62335 |
ACO1
Grp94 inhibitor
|
ACO1 is a potent, selective Grp94 inhibitor with IC50 of 0.44 uM, displays >200-fold selectivity against other Hsp90 isoforms. |
PC-61958 |
TAS-116
|
TAS-116 (Pimitespib, TAS116) is a novel potent, selective, orally available HSP90α/β inhibitor with Ki of 34.7, 21.3, >50,000, and >50,000 nM for HSP90α, HSP90β, GRP94, and TRAP1, respectively. |
PC-61250 |
KW-2478
|
KW-2478 (KW2478) is a novel potent Hsp90 inhibitor with IC50 of 3.8 nM (Hsp90α), exhibits antitumor activities both in vitro and in vivo. |
PC-70347 |
STA 2842
|
STA 2842 (STA2842) is a highly specific inhibitor of HSP90 (IC50=135 nM, HSP90α) that competitively binds the N-terminal ATP pocket of HSP90. |
PC-61032 |
4-Br-BnIm
|
4-Br-BnIm is a potent, subtype-selective Grp94 inhibitor with Kd of 0.96 uM, 13-fold selectivity over Hsp90α. |
PC-60683 |
SNX-0723
|
SNX-0723 is a selective, brain-permeable, orally acitve small-molecule inhibitor of Hsp90 (IC50=14 nM) that inhibits alpha-synuclein oligomerization with EC50 of 48 nM. |
PC-60545 |
Arimoclomol maleate
|
Arimoclomol maleate (BRX-220) is a nontoxic, orally active heat shock protein (HSP) coinducer and potentiator of the heat shock response. |
PC-60544 |
Arimoclomol
|
Arimoclomol (BRX-220) is a nontoxic heat shock protein (HSP) coinducer and potentiator of the heat shock response. |
PC-60497 |
SM253
HSP90 inhibitor
|
SM253 (SM 253, SM-253) is a novel potent Hsp90 inhibitor that does not induce heat shock response. |
PC-60471 |
MPC-3100
HSP90 inhibitor
|
MPC-3100 is a novel potent, selective, orally bioavailable Hsp90 inhibitor with IC50 of 0.14 uM. |
PC-60470 |
MPC-0767
|
MPC-0767 (MPC0767, MPC3100 mesylate hydrate) is an L-alanine ester prodrug of MPC-3100, which is a potent, selective, orally bioavailable Hsp90 inhibitor with IC50 of 0.14 uM. |
PC-60233 |
CCT-251236
|
CCT251236 (CCT-251236) is a potent, orally available Pirin ligand (Ki=28 nM), blocks the HSF1-mediated induction of both HSP72 and HSP27. |