| Cat. No. |
Product Name |
Information |
| PC-60028 |
A-485
p300/CBP inhibitor
|
A-485 (A485) is a potent, selective and, cell and in vivo active p300/CBP catalytic inhibitor with IC50 of 9.8/2.6 nM. |
| PC-45646 |
I-CBP112
CBP/p300 inhibitor
|
I-CBP112 is a specific and potent inhibitor of CBP/p300 bromodomain with Kd of 150-170 nM. |
| PC-21986 |
EPIC-0628
HOTAIR-EZH2 inhibitor
|
EPIC-0628 (EPIC0628) is a selective and potent inhibitor that selectively disrupts the HOTAIR-EZH2 interaction and promotes ATF3 expression, enhances the temozolomide efficacy in glioblastoma. |
| PC-21843 |
SGF29 inhibitor DC60
SGF29 inhibitor
|
SGF29 inhibitor DC60 is a small molecule inhibitor of Spt-Ada-Gcn5 acetyltransferase (SAGA)-associated factor 29 (SGF29, CCDC101) with IC50 of 6.4 uM, binds to SGF29 second Tudor domain (SGF29 Tudor 2) and blocks SGF29 chromatin binding domain. |
| PC-20867 |
MG149
Tip60 (KAT5) inhibitor
|
MG149 is a selective histone acetyltransferase Tip60 (KAT5) inhibitor with IC50 of 74 uM, with no activity against PCAF and p300. |
| PC-20778 |
C646
p300 inhibitor
|
C646 is a selective, competitive histone acetyltransferase (HAT) p300 inhibitor with Ki of 400 nM, less potent for other acetyltransferases. |
| PC-20777 |
MC4171
KAT8 inhibitor
|
MC4171 (KAT8 inhibitor 34) is a first-in-class, selective and reversible lysine acetyltransferase KAT8 inhibitor with IC50 of 8.1 uM and SPR Kd of 2.04 uM. |
| PC-49530 |
DS-9300
EP300/CBP inhibitor
|
DS-9300 (DS9300) is a highly potent, selective and orally active EP300/CBP histone acetyltransferase (HAT) inhibitor with IC50 of 28 nM, inhibits cellular acetylation of histone H3K27 (H3K27Ac) with IC50 of 54 nM. |
| PC-72364 |
Cholera Toxin B subunit
p300 activator
|
Cholera Toxin B subunit (CTB) is a small molecule activator of p300 HAT enzyme, stimulats the expression of p300. |
| PC-72239 |
CCT077791
PCAF inhibitor
|
CCT077791 (CCT077791) is a small molecule inhibitor of PCAF and p300 histone acetyltransferase with IC50 of 2.2 uM and IC95 of 35 uM, respectively. |
| PC-72165 |
CPI-1612
EP300/CBP inhibitor
|
CPI-1612 (CPI 1612) is a highly potent, selective, orally bioavailable EP300/CBP histone acetyltransferase inhibitor with IC50 of 8.1 nM (EP300 HAT SPA). |
