| Cat. No. |
Product Name |
Information |
| PC-70359 |
TM2-115
|
TM2-115 is a BIX-01294 derivative that inhibit malaria parasite histone methyltransferases, resulting in rapid and irreversible parasite death. |
| PC-61030 |
EZM 2302
CARM1 inhibitor
|
EZM 2302 (EZM2302, GSK 3359088) is a potent, selective, orally available arginine methyltransferase CARM1 inhibitor with IC50 of 6 nM, with broad selectivity against other HMTases. |
| PC-60541 |
(R)-OR-S1
|
(R)-OR-S1 is a potent, selective, orally bioavailable EZH1/2 dual inhibitor with IC50 of 7.4/10 nM, inhibits H3K27me3 in HCT116 cells with IC50 of 0.47 nM. |
| PC-60423 |
A-893
|
A-893 (A893) is a potent, selective and cell active lysine methyltransferase SMYD2 inhibitor with IC50 of 2.8 nM. |
| PC-60420 |
BAY-598
|
BAY-598 (BAY598) is a potent, selective, and cell-active, substrate-competitive inhibitor of SMYD2 with IC50 of 27±7 nM in the biochemical SPA assay. |
| PC-70164 |
EML-633
SPIN1 inhibitor
|
EML-633 (EML633) small-molecule inhibitor of methyllysine reader protein SPIN1 (Spindlin 1) with Kd of 2 uM. |
| PC-70163 |
EML-631
SPIN1 inhibitor
|
EML-631 (EML631) is a small-molecule inhibitor of the methyl-lysine reader protein Spindlin1 (SPIN1) with Kd of 4 uM. |
| PC-70162 |
EML-405
SPIN1 inhibitor
|
EML-405 (EML405) is a small-molecule inhibitor of the methyl-lysine reader protein Spindlin1 (SPIN1) with Kd of 14 uM. |
| PC-70161 |
UNC-1679
L3MBTL3 inhibitor
|
UNC-1679 (UNC1679) is a potent and selective small molecule chemical probe of a methyl-lysine reader protein L3MBTL3 with Ki of 0.35 uM. |
| PC-70114 |
MM-401
MLL1/WDR5 inhibitor
|
MM-401 is a potent inhibitor of MLL1/WDR5 protein-protein interaction with IC50 of 0.9 nM. |
| PC-70109 |
GSK-2807
|
GSK-2807 (GSK 2807, GSK2807) is a potent and selective, SAM-competitive inhibitor of SMYD3 with Ki of 14 nM. |
| PC-70108 |
BCI-121
SMYD3 inhibitor
|
BCI-121 (BCI121) is a substrate-competitive SMYD3 inhibitor that significantly inhibits SMYD3-substrate interaction and chromatin recruitment and is effective in reducing proliferation in various cancer cells types. |
