| Cat. No. |
Product Name |
Information |
| PC-42796 |
GNE-477
PI3K/mTOR inhibitor
|
GNE-477 is a potent, dual PI3K/mTOR inhibitor with IC50 of 4 nM for PI3Kα, Ki of 21 nM for mTOR. |
| PC-42328 |
PI-103
PI3K/mTOR inhibitor
|
PI-103 is a potent, dual class I PI3K/mTOR inhibitor with IC50 of 2/3/3/15/ for p110α/β/δ/γ, respectively. |
| PC-45837 |
Dactolisib
PI3K/mTOR inhibitor
|
Dactolisib (NVP-BEZ235) is a potent, dual ATP-competitive pan-class I PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR(p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM, respectively. |
| PC-45071 |
Seletalisib
PI3Kδ inhibitor
|
Seletalisib (UCB-5857) is a potent, ATP-competitive, and selective PI3Kδ inhibitor with IC50 of 12 nM. |
| PC-42442 |
Wortmannin
PI3K inhibitor
|
Wortmannin (SL-2052, KY-12420) is a potent PI3K inhibitor with IC50 of 3 nM, does not inhibit PI4K activity. |
| PC-42925 |
PI-3065
p110δ inhibitor
|
PI-3065 is a potent inhibitor of PI3K p110δ with IC50/Ki values of 5/1.5 nM respectively. |
| PC-45869 |
ZSTK-474
PI3K inhibitor
|
ZSTK-474 (ZSTK474) is a potent inhibitor of class I PI3K isoforms with IC50 of 17 nM, 53 nM, and 6 nM for p110β, p110γ, and p110δ, respectively. |
| PC-42695 |
PKI-402
PI3K/mTOR inhibitor
|
PKI-402 is a potent dual PI3K/mTOR inhibitor with IC50 of 1/7/16/14/1.7 nM for PI3Kα/β/γ/δ/mTOR respectively. |
| PC-42315 |
IC-87114
PI3Kδ inhibitor
|
IC-87114 (IC87114) is a potent and selective PI3Kδ inhibitor with IC50 of 0.5 uM. |
| PC-42326 |
SF2523
PI3K/BRD4 inhibitor
|
SF2523 is a potent, dual inhibitor of PI3K and BRD4 with IC50 of 241, 34, 158 nM for BRD4 (BD1), PI3Kα and PI3Kγ, respectively. |
| PC-45394 |
Leniolisib
PI3Kδ inhibitor
|
Leniolisib (CDZ173) is a potent and selective PI3Kδ inhibitor with biochemical IC50 of 11 nM. |
| PC-42518 |
PIK-294
p110δ inhibitor
|
PIK-294 is a highly potent, selective p110δ inhibitor with IC50 of 10 nM, shows 1000-, 49- and 16-fold less potent to PI3Kα/β/γ. |
