Cat. No. |
Product Name |
Information |
PC-60965 |
PR-825
|
A potent, specific immunoproteasome β5 subunit inhibitor.. |
PC-60963 |
PR-924
|
A potent, specific immunoproteasome LMP7 subunit inhibitor with IC50 of 25 nM, >100-fold selectivity over β5c, β1i, β1c, β2i and β2c subunits (IC50>3 uM). |
PC-60476 |
FV-162
|
A potent, orally bioavailable, irreversible proteasome inhibitor with potent antimyeloma activity (IC50<60 nM). |
PC-42596 |
MLN2238
|
A potent, selective, orally bioavailable proteasome inhibitor with IC50 of 3.4 nM. |
PC-45704 |
PD-151746
|
A potent, selective, cell-permeable Calpain inhibitor with Ki of 0.26 uM for m-calpain. |
PC-42597 |
Delanzomib
|
A potent, orally active proteasome inhibitor with IC50 of 3.8 nM against chymotrypsin-like proteasome activity. |
PC-45547 |
VR-23
|
A potent inhibitor of trypsin-like proteasome (IC50=1 nM), chymotrypsin-like proteasome (IC50=50-100 nM) and caspase-like proteasome (IC50=3 uM). |
PC-45577 |
MG-101
|
A potent inhibitor of cysteine proteases including calpain I (Ki= 190 nM), calpain II (Ki= 220 nM), cathepsin B (Ki= 150 nM) and cathepsin L (Ki= 500 pM). |
PC-42190 |
PD-150606
|
A potent and selective calpain inhibitor with Ki of 0.21 uM/0.37 uM for u-calpain/m-calpain, respectively. |