| Cat. No. |
Product Name |
Information |
| PC-49668 |
WNN2048-F004
SARS-CoV-2 Mpro inhibitor
|
WNN2048-F004 (Compound 4a) is a potent, covalent, nonpeptidomimetic SARS-CoV-2 main protease (Mpro) inhibitor with biochemical IC50 of 103 nM, covalently binds to the substrate-binding pocket (Cys145) of SARS-CoV-2 Mpro. |
| PC-49579 |
Mpro inhibitor GD-9
SARS-CoV-2 Mpro inhibitor
|
Mpro inhibitor GD-9 is a potent, covalent SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 0.18 uM, exhibits antiviral potency against SARS-CoV-2 with EC50 of 2.64 uM. |
| PC-49528 |
DMGA
SARS-CoV-2 PLpro inhibitor
|
DMGA is an allosteric and covalent inhibitor of SARS-CoV-2 papain-like protease (SARS-CoV-2 PLpro) with IC50 of 9.4 uM, covalently binds with C270 of the SARS-CoV-2 PLpro. |
| PC-49424 |
Difluorobenztropine
|
Difluorobenztropine (AHN 1-055) is a direct-acting SARS-CoV-2 entry inhibitor that targets the SARS-CoV-2 spike fusion peptide domain. |
| PC-49423 |
TMPRSS2 inhibitor BC-11
TMPRSS2 inhibitor
|
TMPRSS2 inhibitor BC-11 is a specific, covalent transmembrane protease serine 2 (TMPRSS2) inhibitor with IC50 of 1.44 uM in vitro TMPRSS2 enzymatic assay. |
| PC-49342 |
GC-14
SARS-CoV-2 Mpro inhibitor
|
GC-14 is a potent, selective and non-covalent non-peptide SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 0.4 uM, displays excellent selectivity over cathepsins B, F, K, L, and caspase 3 (IC50>50 uM). |
| PC-49327 |
KSL 128114
Syntenin inhibitor
|
KSL-128114 (KLS 128114) is a highly potent and metabolically stable peptide inhibitor that binds to the PDZ1 domain of syntenin (KD=0.3 uM), inhibits SARS-CoV-2 infection by blocking the endosomal entry of the virus. |
| PC-49258 |
AB-00011778
SARS-CoV-2 entry inhibitor
|
AB-00011778 is a small molecule inhibitor of SARS-CoV-2 entry and the Spike/ACE2 interaction, inhibits viral replication with EC50 of 250 nM in A549-ACE2 cells, AB-00011778 is equally effective in impairing the S/ACE2 association in the different mutants. |
| PC-47020 |
Nafamostat mesylate
SARS-CoV-2 Inhibitor
|
Nafamostat mesylate is a synthetic serine protease inhibitor with anticoagulant, anti-inflammatory, mucus clearing, and potential antiviral activities, blocked SARS-CoV-2 infection of Calu-3 cells with IC50 of 10 nM. |
| PC-38897 |
VE607
SARS-CoV entry inhibitor
|
VE607 is a specific small molecule inhibitor that block S protein-ACE2-mediated cellular entry of the SARS-CoV, inhibits pseudovirus entry with EC50 of 3 μM and inhibited SARS-CoV plaque formation with EC50 of 1.6 μM. |
| PC-38708 |
ALG-097111
SARS-CoV-2 3CLpro inhibitor
|
ALG-097111 is a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease (3CLpro) with IC50 of 7 nM, without effect against human cathepsin L (IC50>10 uM). |
| PC-38568 |
SSAA09E3
SARS CoV entry inhibitor
|
SSAA09E3 is a small molecule inhibitor of SARS coronavirus with EC50 of 0.15 uM in infectious virus assay in Vero cells, preventing fusion of the viral membrane with the host cellular membrane. |
