| Cat. No. |
Product Name |
Information |
| PC-60554 |
ME-344
mTOR inhibitor
|
ME-344 is a novel mitochondrial and mTOR inhibitor with potent anti-cancer activity, inhibits leukemia cell lines with IC50 of 70-260 nM. |
| PC-60482 |
AZD3147
mTOR inhibitor
|
AZD3147 is a potent, selective dual mTORC1 and mTORC2 inhibitor with enzyme IC50 of 1.5 nM. |
| PC-60418 |
RapaLink-1
mTOR inhibitor
|
RapaLink-1 is a third-generation mTOR inhibitor that overcomes resistance to existing first- and second-generation inhibitors. |
| PC-60132 |
Temsirolimus
mTOR inhibitor
|
Temsirolimus (CCI779, Torisel) is a rapamycin ester and mTOR inhibitor with biochemical IC50 of 1.74 uM. |
| PC-45649 |
Seco Rapamycin sodium salt
|
Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin that does not affect mTOR.. |
| PC-45851 |
KU-0063794
mTOR inhibitor
|
KU-0063794 is a potent, specific, cell permeant inhibitor of mTOR with IC50 of 10 nM for both mTORC1 and mTORC2. |
| PC-42157 |
WYE-125132
mTOR inhibitor
|
A potent, specific, ATP-competitive and orally active mTOR inhibitor with IC50 of 0.19 nM. |
| PC-42608 |
PP 242
mTOR inhibitor
|
Torkinib (PP242) is a potent, specific active-site inhibitor of mTOR with IC50 of 30 and 58 nM for mTORC1 and mTORC2, respectively. |
| PC-42576 |
AZD-8055
mTOR inhibitor
|
AZD-8055 is a potent, selective, ATP-competitive and orally bioavailable mTOR inhibitor with IC50 of 0.8 nM. |
| PC-45098 |
CC-223
mTOR inhibitor
|
CC-223 is a potent, selective, and orally bioavailable inhibitor of mTOR kinase with IC50 of 16 nM. |
| PC-45902 |
Deforolimus
mTOR inhibitor
|
Deforolimus (AP-23573, MK-8669, Ridaforolimus) potent, selective mTOR inhibitor with IC50 of 0.2 nM in HT-1080 cell line. |
| PC-42463 |
Everolimus
mTOR inhibitor
|
Everolimus (RAD001) is a potent, highly specific, orally active mTOR inhibitor with IC50 of 5-6 nM for binding to FKBP-12 or FKBP-12 complexed to mTOR. |
