| Cat. No. |
Product Name |
Information |
| PC-62439 |
AMG-548
|
AMG-548 is a potent and selective inhibitor of p38α with Ki of 0.5 nM, dispalys weak inhibition for p38β (Ki=3.6 nM), and >5,000-fold selectivity over p38γ and p38δ. |
| PC-61210 |
SC-806
|
A potent, orally active p38 MAPK inhibitor with IC50 of 50 nM, significantly decreases incidence of
arthritis in mouse collagen-induced arthritis.. |
| PC-61001 |
AS1940477
|
A potent, selective, orally active p38α/p38β inhibitor with IC50 of 11.2/36.5 nM respectively, with no effect on p38γ and δ isoforms (IC50>1 uM). |
| PC-60432 |
MW-150 hydrochloride
|
A novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM. |
| PC-70148 |
CMPD-1
|
A potent, selective, non-ATP-competitive inhibitor of p38α-mediated MK2a phosphorylation with apparent Ki of 330 nM. |
| PC-45059 |
Acumapimod
|
An orally active, potent p38 MAPK inhibitor that potently inhibits ex vivo LPS‐induced TNFα secretion with an IC50 of 44 ng/mL (115 nM). |
| PC-42492 |
SB 203580 hydrochloride
|
A specific p38 MAPK inhibitor with IC50 of 0.6 uM. |
| PC-45452 |
SB-242235
|
A selective p38 MAPK inhibitor. |
| PC-42803 |
SB 239063
|
A potent, selective, orally available p38 MAPK inhibitor with IC50 of 44 nM for both p38α and p38β. |
| PC-42599 |
TAK-715
|
A potent, selective, orally active p38α MAPK inhibitor with IC50 of 7.1 nM. |
| PC-42662 |
PD 169316
|
A potent, selective p38 MAPK inhibitor with IC50 of 89 nM. |
| PC-42059 |
TA-02
|
A potent p38 MAPK inhibitor with IC50 of 20 nM. |
