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Werner syndrome RecQ helicase-IN-3

Chemical Structure : Werner syndrome RecQ helicase-IN-3

CAS No.: 2869954-98-1

Werner syndrome RecQ helicase-IN-3

Catalog No.: PC-20676Not For Human Use, Lab Use Only.

Werner syndrome RecQ helicase-IN-3 is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor with IC50 of 60 nM for WRN ATPase.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Werner syndrome RecQ helicase-IN-3 is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor with IC50 of 60 nM for WRN ATPase.

Physicochemical Properties

M.Wt 687.07
Formula C31H30ClF3N8O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

O=C(N1CCN(CC1)C2=C(CC)N(CC(NC3=CC=C(C(F)(F)F)C=C3Cl)=O)C4=NC(C5=CCOCC5)=NN4C2=O)C6=NC=CC=C6O

References

1. Patent WO2022249060A1.

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