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Cat. No. Product Name Information
PC-72267

CU7218

CU7218 is a small-molecule inhibitor of 14-3-3 protein, inhibits the interaction between 9J10 and 14-3-3.
PC-61231

14-3-3 inhibitor BV02

14-3-3 inhibitor BV02 is a novel nonpeptidic inhibitor of 14-3-3 protein-protein interaction that promotes the apoptotic death of cells expressing either wt Bcr-Abl construct or T315I mutation.
PC-38502

HS-1793

HS-1793 is a resveratrol derivative that overcomes the resistance conferred by Bcl-2 in U937 cells via 14-3-3, exhibits antitumor activity via Bad and marked downregulates 14-3-3 protein.
PC-62030

FOBISIN 101

FOBISIN 101 is a small molecule 14-3-3 protein-protein interaction inhibitor with IC50 of 9.3 and 16.4 uM for the binding of 14-3-3ζ or 14-3-3γ to PRAS40, respectively.
PC-61238

RB-011

A small molecule that disrupt 14-3-3 dimers at low micromolar concentrations and induce rapid down-regulation of Raf-MAPK and PI3K-Akt signaling in Jurkat cells.
PC-61233

Fusicoccin-A

A small-molecule stabilizer of 14-3-3 protein-protein interactions that stabilizes the complex between 14-3-3 and the stress response regulator GCN1.
PC-61232

Difopein

A specific, competitive inhibitor of 14-3-3/ligand interactions with high affinity.

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