| Cat. No. |
Product Name |
Information |
| PC-72267 |
CU7218
|
CU7218 is a small-molecule inhibitor of 14-3-3 protein, inhibits the interaction between 9J10 and 14-3-3. |
| PC-61233 |
Fusicoccin-A
|
Fusicoccin-A is a small-molecule stabilizer of 14-3-3 protein-protein interactions that stabilizes the complex between 14-3-3 and the stress response regulator GCN1. |
| PC-61231 |
14-3-3 inhibitor BV02
|
14-3-3 inhibitor BV02 is a novel nonpeptidic inhibitor of 14-3-3 protein-protein interaction that promotes the apoptotic death of cells expressing either wt Bcr-Abl construct or T315I mutation. |
| PC-21138 |
14-3-3σ/ERα stabilizer 181
|
14-3-3σ/ERα stabilizer 181 is a selective and highly potent covalent stabilizer of 14-3-3σ/ERα PPI complex with EC50 of 1 uM. |
| PC-38502 |
HS-1793
|
HS-1793 is a resveratrol derivative that overcomes the resistance conferred by Bcl-2 in U937 cells via 14-3-3, exhibits antitumor activity via Bad and marked downregulates 14-3-3 protein. |
| PC-62030 |
FOBISIN 101
|
FOBISIN 101 is a small molecule 14-3-3 protein-protein interaction inhibitor with IC50 of 9.3 and 16.4 uM for the binding of 14-3-3ζ or 14-3-3γ to PRAS40, respectively. |
| PC-61238 |
RB-011
|
A small molecule that disrupt 14-3-3 dimers at low micromolar concentrations and induce rapid down-regulation of Raf-MAPK and PI3K-Akt signaling in Jurkat cells. |
