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Request The Product List ofATM/ATR ATM/ATR

Cat. No. Product Name Information
PC-73375

M3541

ATM inhibitor

M3541 (M 3541) is a novel potent, selective and ATP-competitive ATM kinase inhibitor with IC50 of 0.25 nM (ATP, 10 uM).
PC-72900

M4076

ATM inhibitor

Lartesertib (M4076) is a higly potent, selective, ATP-competitive inhibitor of ATM kinase with IC50 of 0.2 nM.
PC-72315

RP-3500

ATR inhibitor

RP-3500 (RP3500, Camonsertib) is a novel potent, selective, orally bioavailable ATR inhibitor with IC50 of 1.0 and 0.33 nM in biochemical and cell-based assays, respectively.
PC-72164

Berzosertib

ATR inhibitor

Berzosertib (M6620, VX-970, VE-822) is a highly potent, selective ATR inhibitor with Ki of 0.17 nM, pH2AX IC50 of 19 nM.
PC-72163

M4344

ATR inhibitor

M4344 (VX-803, Gartisertib) is a highly potent, selective ATR inhibitor with Ki<0.15 nM.
PC-42876

KU-60019

ATM inhibitor

KU-60019 is an improved analogue of KU-55933, and is a potent, specific inhibitor of ATM kinase with IC50 of 6.3 nM, 270- and 1,600-fold selectivity over DNA-PKcs and ATR.
PC-42831

KU-55933

ATM inhibitor

KU-55933 (KU55933) is a potent, specific, ATP-competitive inhibitor of ATM with Ki/IC50 of 2.2/13 nM, >100-fold selectivity against other members of the PIKK family kinases.
PC-61826

AZD1390

ATM inhibitor

AZD1390 (AZD-1390) is a novel potent, selective, orally available and CNS penetrant ATM inhibitor with IC50 of 0.78 nM, displays >1,000-fold selectivity over closely related (PIKKs) and distant kinases.
PC-70146

BAY-1895344 hydrochloride

ATR inhibitor

BAY-1895344 (Elimusertib) hydrochloride is a potent, selective, orally active ATR inhibitor with low-nanomolar potency (IC50=7 nM).
PC-60277

BAY-1895344

ATR inhibitor

BAY 1895344 (BAY1895344, Elimusertib) is a novel potent, highly selective ATR kinase inhibitor with IC50 of 7.0 nM.
PC-44042

VE-821

ATR inhibitor

VE-821 (VE821) is a potent, selective and ATP-competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM, respectively.
PC-42030

AZD-0156

ATM inhibitor

AZD-0156 (AZD0156, AZD 0156) is a potent, highly selective and orally bioavailable ATM kinase inhibitor with IC50 of 0.58 nM.

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