| Cat. No. |
Product Name |
Information |
| PC-73375 |
M3541
|
M3541 (M 3541) is a novel potent, selective and ATP-competitive ATM kinase inhibitor with IC50 of 0.25 nM (ATP, 10 uM). |
| PC-72900 |
M4076
|
Lartesertib (M4076) is a higly potent, selective, ATP-competitive inhibitor of ATM kinase with IC50 of 0.2 nM. |
| PC-72315 |
RP-3500
|
RP-3500 (RP3500, Camonsertib) is a novel potent, selective, orally bioavailable ATR inhibitor with IC50 of 1.0 and 0.33 nM in biochemical and cell-based assays, respectively. |
| PC-72164 |
M6620
|
M6620 (Berzosertib, VX-970, VE-822) is a highly potent, selective ATR inhibitor with Ki of 0.17 nM, pH2AX IC50 of 19 nM. |
| PC-72163 |
M4344
|
M4344 (VX-803, Gartisertib) is a highly potent, selective ATR inhibitor with Ki<0.15 nM. |
| PC-61826 |
AZD1390
|
AZD1390 (AZD-1390) is a novel potent, selective, orally available and CNS penetrant ATM inhibitor with IC50 of 0.78 nM, displays >1,000-fold selectivity over closely related (PIKKs) and distant kinases. |
| PC-70146 |
BAY-1895344 hydrochloride
|
BAY-1895344 is a potent, selective, orally active ATR inhibitor with low-nanomolar potency. |
