| Cat. No. |
Product Name |
Information |
| PC-72818 |
IMA-1
|
IMA-1 (ALOX12-ACC1 inhibitor IMA-1) is a small molecule that interrupt the arachidonate 12-lipoxygenase (ALOX12)-acetyl-CoA carboxylase 1 (ACC1) interaction. |
| PC-72388 |
PF-05221304
|
PF-05221304 (PF 05221304) is a novel potent, selective, liver-targeted dual acetyl-CoA carboxylase (ACC1/2) inhibitor with IC50 of 13/9 nM (hACC1/2). |
| PC-63466 |
PF-05175157
|
PF-05175157 (PF-5175157) is a potennt Acetyl-CoA carboxylase (ACC) inhibitor with IC50 of 27 and 33 nM for hAAC1 and hACC2, respectively. |
| PC-61377 |
Firsocostat
|
Firsocostat (ND-630, NDI-010976, GS-0976) is a highly potent, selective inhibitor of acetyl-CoA carboxylase (ACC) with IC50 of 2.1 and 6.1 nM for isozymes ACC1 and ACC2, respectively. |
| PC-42306 |
TOFA
|
TOFA (RMI14514, MDL14514) is an indirect, allosteric inhibitor of Acetyl-CoA carboxylase-α (ACCA) and fatty acid synthesis. |
| PC-43001 |
ETC-1002
|
ETC-1002 (ESP-55016; Bempedoic acid) is a small molecule regulator of lipid and carbohydrate metabolism that targets ACC (acetyl-CoA carboxylase) with IC50 of 29 uM without activating the AMPK pathway in vitro. |
| PC-20376 |
ND-646
|
ND-646 (ND646) is a potent, selective and allosteric inhibitor of acetyl-CoA carboxylase ACC1 and ACC2 with IC50 of 3.5 and 4.2 nM for hACC1 and hACC2, respectively. |
