| Cat. No. |
Product Name |
Information |
| PC-49073 |
VP15 hydrochloride
AChE inhibitor
|
VP15 hydrochloride (VP-15 HCl) is a BBB-penetrant, orally active, multitarget directed ligand against acetylcholine and monoamine oxidase enzymes with IC50 of 0.04 and 0.37 uM for AChE and MAO-B, respectively, >600-fold selectivity over BuChE. |
| PC-63361 |
Zanapezil
AChE inhibitor
|
Zanapezil (TAK-147) is a potent, selective acetylcholinesterase (AChE) inhibitor with IC50 of 97.7 nM. |
| PC-62461 |
Ipidacrine
AChE inhibitor
|
Ipidacrine is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. |
| PC-62460 |
Ipidacrine hydrochloride
AChE inhibitor
|
Ipidacrine hydrochloride is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. |
| PC-61035 |
TAK-802
AChE inhibitor
|
TAK-802 is potent acetylcholinesterase (AChE) inhibitor with IC50 of 1.3 nM. |
| PC-22544 |
UW-MD-95
BChE inhibitor
|
UW‐MD‐95 is a potent pseudo‐irreversible butyrylcholinesterase (BChE) inhibitor with IC50 of 60 nM, does not inhibit AChE, shows potent neuroprotective in the Aβ25‐35 model of AD. |
| PC-22297 |
S21-1011
BChE inhibitor
|
S21-1011 is a potent, selective, BBB-penetrant butyrylcholinesterase (BChE) inhibitor with IC50 of 59 nM and 162 nM for eqBChE and hBChE, respectively. |
| PC-61036 |
TAK-802 hydrochloride
|
A potent acetylcholinesterase (AChE) inhibitor with IC50 of 1.3 nM. |
| PC-60067 |
AD-35 hydrochloride
|
A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates. |
| PC-60066 |
AD-35
|
A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates. |
| PC-60065 |
AD-35 phosphate
|
A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates. |
| PC-42789 |
Rivastigmine tartrate
|
An acetylcholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase. |
