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Cat. No. Product Name Information
PC-49355

ALM301

ALM301 is a potent, selective and allosteric inhibitor of AKT1 and AKT2 with IC50 of 125 nM and 95 nM respectively.
PC-49017

Ipatasertib

Ipatasertib (GDC-0068) is a potent, selective, orally bioavailable pan-Akt inhibitor with IC50 values of 5 nM, 18 nM, and 8 nM for Akt1, Akt2, and Akt3, respectively.
PC-38198

TAS0612

TAS0612 (TAS-0612) is an orally bioavailable multikinase inhibitor of AKT, p70S6K, and p90RSK, inhibits Y-box-binding protein (YBX1) phosphorylation.
PC-36126

Borussertib

Borussertib is a potent, first-in-class, covalent-allosteric AKT inhibitor with IC50 of 0.8 nM and Ki of 2.2 nM for WT Akt.
PC-43433

A-674563

A-674563 is a potent, selective and orally available AKT inhibitor with Ki of 11 nM (Akt1).
PC-61416

LY2780301

LY2780301 is a potent, highly selective, ATP-competitive dual inhibitor of p70S6K and Akt under development for the treatment of solid tumours and non-Hodgkin's lymphoma.
PC-45548

SC-79

SC-79 is a unique specific Akt activator, binds to the PH domain of Akt and inhibits Akt membrane translocation, but paradoxically activates Akt in the cytosol.

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