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Cat. No. Product Name Information


ALDH1A3 inhibitor

KOTX1 is a potent, selective and reversible ALDH1A3 inhibitor with IC50 of 5.14 nM by Aldefluor assay in A375 cells.


ALDH1A3 inhibitor

ER-001135935 is a potent selective inhibitor of aldehyde dehydrogenase family 1 member A3 (ALDH1A3) with IC50 of 64 nM, Ki value of 106 nM.

ALDH1A3 inhibitor NR6

ALDH1A3 inhibitor

ALDH1A3 inhibitor NR6 is a specific ALDH1A3 inhibitor with IC50 of 5.3 uM and Ki of 3.7 uM, high selective over ALDH1A1 and ALDH1A2.

ALD1A3 inhibitor CB7

ALDH1A3 inhibitor

ALD1A3 inhibitor CB7 is a highly selective inhibitor of ALDH3A1 with IC50 of 0.2 uM, does not inhibit ALDH1A1, ALDH1A2, ALDH1A3, ALDH1B1, or ALDH2 activity.

ALDH1A1 inhibitor N42

ALDH1A1 inhibitor

ALDH1A1 inhibitor N42 (FSI-TN42) is a potent, specific and orally bioavailable ALDH1A1 inhibitor with IC50 of 23 nM, 800-fold selectivity over ALDH1A2 (IC50=18 uM).


ALDHs chemical probe

STA-55 is a broad-spectrum activity-based probe of aldehyde dehydrogenase family (ALDHs), can be used to identify therapy resistance biomarkers in cancer and to validate target engagement of ALDH drug candidates.


ALDHs chemical probe

LEI-945 (LEI 945) is a first-in-class probe that enables profiling retinaldehyde dehydrogenases (ALDHs) in cancer cells.

ALDH1A1 inhibitor CM37

ALDH1A1 inhibitor

ALDH1A1 inhibitor CM37 is a selective and competitive inhibitor of ALDH1A1 with Ki of 300 nM, shows minimal inhibitory effects for ALDH1A2, ALDH1A3, ALDH2, or ALDH3A1 at 20 uM.

ALDH1A1 inhibitor 974

ALDH1A1 inhibitor

ALDH1A1 inhibitor 974 (Compound 974) is a first-in-class, highly potent and specific ALDH1A1 inhibitor with IC50 of 470 nM, suppresses chemotherapy-induced senescence as well as stemness.


ALDH1B1 inhibitor

IGUANA-1 is a potent, isoform-selective inhibitor of aldehyde dehydrogenase ALDH1B1, exhibits proteome-wide target specificity, and selectively blocks the growth of colon cancer spheroids and organoids.


ALDH1A3 inhibitor

MCI-INI-3 is a potent, selective, competitive inhibitor of ALDH1A3 (Ki=0.55 uM, shows poor inhibitory effect on the structurally related isoform ALDH1A1 (>140-fold selectivity).


ALDH1A inhibitor

Dichloro-all-trans-retinone (DAR) is an irreversible inhibitor of retinaldehyde dehydrogenase (RALDH/ALDH1A) with IC50 of 434/55/161 nM for RALDH1/RALDH2/RALDH3.

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