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Cat. No. Product Name Information
PC-49597A

UT-215

UT-215 (UT215) is a small-molecule selective androgen receptor (AR) irreversible covalent antagonist, covalently and selectively bind to C406 and C327 in the AF-1 region of AR.
PC-20115

ET516

ET516 is a potent androgen receptor liquid-liquid phase separation (AR LLPS) inhibitor, specifically disrupts AR condensates, effectively suppresses AR transcriptional activity and inhibits the proliferation and tumor growth of prostate cancer cells expressing AR-resistant mutants.
PC-49597

UT-143

UT-143 (UT143) is a small-molecule selective androgen receptor (AR) irreversible covalent antagonist, covalently and selectively bind to C406 and C327 in the AF-1 region of AR.
PC-49173

JJ-450

JJ-450 is a novel analogue of IMTPPE and direct and specific inhibitor of androgen receptor (AR) transcriptional activity, blocks AR recruitment to androgen-responsive elements and suppresses AR target gene expression.
PC-72753

VPC-13789

VPC-13789 (VPC13789) is a potent, selective, orally available inhibitor of androgen receptor binding function-3 (BF3) site with IC50 of 0.19 uM.
PC-72511

JNJ-63576253

JNJ-63576253 (TRC-253, JNJ63576253) is a next-generation, potent, selective androgen receptor (AR) antagonist (inhibitor) against wild-type AR (IC50=6.9 nM), AR F877L and other clinically detected ligand binding domain (LBD) point mutations.
PC-35680

KCI807

KCI807 (KCI-807) is a small molecule that selectively disrupts ELK1-dependent promoter activation by wild-type and variant androgen receptors (IC50=0.53 uM) without interfering with ELK1 activation by ERK.

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