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Request The Product List ofAndrogen Receptor (AR) Androgen Receptor (AR)

Cat. No. Product Name Information
PC-22067

SC912

AR-V7 inhibitor

SC912 is a small molecule inhibitor of androgen receptor AR-V7, binds to full-length AR as well as AR-V7 through AR N-terminal domain (AR-NTD), disruptes AR-V7 transcriptional activity, impairs AR-V7 nuclear localization and DNA binding.
PC-21578

AR NTD inhibitor 16

AR NTD inhibitor

AR NTD inhibitor 16 is a small molecule inhibitor of androgen receptor N-terminal domain (AR NTD) with IC50 of 0.12 uM in VCaP cell-based GRE2-luciferase reporter gene assays.
PC-49597A

UT-215

AR antagonist

UT-215 (UT215) is a small-molecule selective androgen receptor (AR) irreversible covalent antagonist, covalently and selectively bind to C406 and C327 in the AF-1 region of AR.
PC-20115

ET516

AR inhibitor

ET516 is a potent androgen receptor liquid-liquid phase separation (AR LLPS) inhibitor, specifically disrupts AR condensates, effectively suppresses AR transcriptional activity and inhibits the proliferation and tumor growth of prostate cancer cells expressing AR-resistant mutants.
PC-20039

Gumelutamide

AR inhibitor

Gumelutamide (TAS3681) is a potent, selective androgen receptor (AR) pure antagonist with Ki of 7.39 and 23.8 nM for WT AR and AR T878A mutant respectively, inhibits AR transcriptional activity and downregulates AR-full length (AR-FL) and AR-Vs.
PC-20032

Faznolutamide

AR inhibitor

Faznolutamide is a potent, selective androgen receptor (AR) antagonist.
PC-49722

RAD140

SARM

Vosilasarm (RAD-140) is a potent, orally bioavailable, nonsteroidal selective androgen receptor modulator (SARM), shows excellent affinity for the androgen receptor (Ki=7 nM).
PC-49597

UT-143

Androgen Receptor inhibitor

UT-143 (UT143) is a small-molecule selective androgen receptor (AR) irreversible covalent antagonist, covalently and selectively bind to C406 and C327 in the AF-1 region of AR.
PC-49412

EPI-7170

AR-NTD inhibitor

EPI-7170 is a potent next-generation analog of Ralaniten (EPI-002) and inhibitor of androgen receptor N-terminal domain (AR-NTD), inhibits androgen-induced PSA-luciferase activity in transiently transfected LNCaP cells with IC50 of 1.08 uM.
PC-49173

JJ-450

AR inhibitor

JJ-450 is a novel analogue of IMTPPE and direct and specific inhibitor of androgen receptor (AR) transcriptional activity, blocks AR recruitment to androgen-responsive elements and suppresses AR target gene expression.
PC-38370

Rezvilutamide

Androgen Receptor inhibitor

Rezvilutamide (SHR3680) is a novel and pure androgen-receptor (AR) antagonist that shows potent antitumor activity against castration-resistant prostate cancer (CRPC) but with much less brain distribution than enzalutamide.
PC-73372

A4B17

BAG1L-AR NTD inhibitor

A4B17 is a small molecule that inhibits BAG1L-AR NTD interaction, inhibits the proliferation of AR positive prostate cancer cells.

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