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Request The Product List ofAutotaxin Autotaxin

Cat. No. Product Name Information
PC-49584

BTT-877

Autotaxin inhibitor

BTT-877 (BTT877) is a potent, selective and orally active inhibitor of autotaxin (ENPP2) with in vitro and ex vivo IC50 of 2.4 nM and 6.89 nM, respectively.
PC-38743

ONO-8430506

Autotaxin inhibitor

ONO-8430506 is a highly potent, orally available autotaxin (ATX) inhibitor with IC50 of 10 nM (recombinant human ATX), exhibits LysoPLD inhibitory activity in human plasma with IC50 of 5.5 nM.
PC-38464

HA155

Autotaxin inhibitor

HA155 is a potent, boronic acid-based autotaxin (ATX) inhibitor with IC50 of 5.7 nM, also used for conjugation to icodextrin.
PC-73412

Cudetaxestat

Autotaxin inhibitor

Cudetaxestat (BLD-0409) is a potent, selective autotaxin (NPP2/ATX) inhibitor under investigation for the treatment of NASH.
PC-72882

Autotaxin-IN-13

Autotaxin inhibitor

Autotaxin-IN-13 ( ATX-i) is a highly potent, selective Autotaxin inhibitor with IC50 of 6 nM.
PC-72060

BIO-32546

Autotaxin inhibitor

BIO-32546 (BIO 32546) is a potent, selective, orally bioavailable, brain-penetrable Autotaxin inhibitor with IC50 of 1 nM.
PC-38008

CRT0273750

Autotaxin inhibitor

CRT0273750 (IOA-289) is a potent, seletive inhibitor of autotaxin with IC50 of 1 nM.
PC-35168

Autotaxin inhibitor 12

Autotaxin inhibitor

Autotaxin inhibitor 12 is a highly potent, selective, orally-bioavailable inhibitor of autotaxin with IC50 of 3.1 nM in choline release assays.
PC-43508

PF-8380

Autotaxin inhibitor

PF-8380 (PF8380) is a potent, specific, orally active Autotaxin inhibitor with IC50 of 2.8 and 101 nM in enzyme assay and in human whole blood assay, respectively.
PC-60695

Autotaxin inhibitor compound 1

Autotaxin inhibitor

Autotaxin inhibitor compound 1 (Autotaxin-IN-1) is a potent, selective, orally bioavailable inhibitor of Autotaxin with IC50 of 2.2 nM in ex vivo human whole blood assay, does not inhibit related proteins ENPP1 and ENPP7.
PC-60640

GWJ-A-23

Autotaxin inhibitor

GWJ-A-23 (GWJ-23, GWJ23) is a potent, selective autotaxin inhibitor with Ki of 18 nM, an analog of the known ATX inhibitor S32826 and has improved aqueous solubility compared with the parent compound.
PC-60639

PAT-048

Autotaxin inhibitor

PAT-048 (PAT048) is a potent, selective, noncompetitive autotaxin inhibitor with IC50 of 1.1 nM against the lysoPLD activity of human ATX.

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