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Request The Product List ofAutotaxin Autotaxin

Cat. No. Product Name Information
PC-38743

ONO-8430506

ONO-8430506 is a highly potent, orally available autotaxin (ATX) inhibitor with IC50 of 10 nM (recombinant human ATX), exhibits LysoPLD inhibitory activity in human plasma with IC50 of 5.5 nM.
PC-73412

Cudetaxestat

Cudetaxestat (BLD-0409) is a potent, selective autotaxin (NPP2/ATX) inhibitor under investigation for the treatment of NASH.
PC-72882

Autotaxin-IN-13

Autotaxin-IN-13 ( ATX-i) is a highly potent, selective Autotaxin inhibitor with IC50 of 6 nM.
PC-38008

CRT0273750

CRT0273750 (IOA-289) is a potent, seletive inhibitor of autotaxin with IC50 of 1 nM.
PC-60695

Autotaxin inhibitor compound 1

Autotaxin inhibitor compound 1 (Autotaxin-IN-1) is a potent, selective, orally bioavailable inhibitor of autotaxin with IC50 of 2.2 nM in ex vivo human whole blood assay, does not inhibit related proteins ENPP1 and ENPP7.
PC-60640

GWJ-A-23

GWJ-A-23 (GWJ-23, GWJ23) is a potent, selective autotaxin inhibitor with Ki of 18 nM, an analog of the known ATX inhibitor S32826 and has improved aqueous solubility compared with the parent compound.
PC-60639

PAT-048

PAT-048 (PAT048) is a potent, selective, noncompetitive autotaxin inhibitor with IC50 of 1.1 nM against the lysoPLD activity of human ATX.

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