| Cat. No. |
Product Name |
Information |
| PC-38743 |
ONO-8430506
|
ONO-8430506 is a highly potent, orally available autotaxin (ATX) inhibitor with IC50 of 10 nM (recombinant human ATX), exhibits LysoPLD inhibitory activity in human plasma with IC50 of 5.5 nM. |
| PC-73412 |
Cudetaxestat
|
Cudetaxestat (BLD-0409) is a potent, selective autotaxin (NPP2/ATX) inhibitor under investigation for the treatment of NASH. |
| PC-72882 |
Autotaxin-IN-13
|
Autotaxin-IN-13 ( ATX-i) is a highly potent, selective Autotaxin inhibitor with IC50 of 6 nM. |
| PC-38008 |
CRT0273750
|
CRT0273750 (IOA-289) is a potent, seletive inhibitor of autotaxin with IC50 of 1 nM. |
| PC-60695 |
Autotaxin inhibitor compound 1
|
Autotaxin inhibitor compound 1 (Autotaxin-IN-1) is a potent, selective, orally bioavailable inhibitor of autotaxin with IC50 of 2.2 nM in ex vivo human whole blood assay, does not inhibit related proteins ENPP1 and ENPP7. |
| PC-60640 |
GWJ-A-23
|
GWJ-A-23 (GWJ-23, GWJ23) is a potent, selective autotaxin inhibitor with Ki of 18 nM, an analog of the known ATX inhibitor S32826 and has improved aqueous solubility compared with the parent compound. |
| PC-60639 |
PAT-048
|
PAT-048 (PAT048) is a potent, selective, noncompetitive autotaxin inhibitor with IC50 of 1.1 nM against the lysoPLD activity of human ATX. |
