You are here:Home-Chemical Inhibitors & Agonists-Apoptosis-Bcl-2

Request The Product List ofBcl-2 Bcl-2

Cat. No. Product Name Information
PC-38808

CCT369260

CCT369260 is a highly potent, orally active BCL6 degrader with DC50 of 54 nM in cellular BCL6 degradation assays.
PC-73236

ZH07

ZH07 (Dual Mcl-1/Bfl-1 inhibitor 24) is a potent, selective dual Mcl-1 and Bfl-1 inhibitor, binds both Mcl-1 and Bfl-1 with Ki of 97 nM and 100 nM, respectively.
PC-72944

BTSA1

BTSA1 (BAX Trigger Site Activator 1) is a potent, selective, orally bioavailable BAX trigger site activator, binds with high affinity (EC50=144 nM) and specificity to the N-terminal activation site.
PC-72943

BTSA1.2

BTSA1.2 is a potent, selective, orally bioavailable BAX activator, demonstrated increased binding to BAX (IC50=149 nM) compared to BTSA1 (IC50=247 nM).
PC-72541

BFL-1 inhibitor 4E14

4E14 (BFL-1 BH3 inhibitor 4E14) is a potent, covalent BFL-1 (BCL2A1 or A1) inhibitor that disrupt BH3-binding activity with IC50 of 23 nM (FITC-BID BH3/BFL-1 interaction).
PC-72311

Lisaftoclax

Lisaftoclax (APG-2575) is a novel BCL-2 selective inhibitor with binding Ki of < 0.1/0.1 nM for Bcl-2/Bcl-XL, no binding affinity against BCL-W/MCL-1.
PC-72240

BAX inhibitor BAI1

BAX inhibitor BAI1 (BAI1) is a small-molecule allosteric inhibitor of BAX, bind directly to BAX and inhibits tBID-induced BAX-mediated membrane permeabilization with IC50 of 3.4 uM.

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com