| Cat. No. |
Product Name |
Information |
| PC-73231 |
GB1874
|
GB1874 is an inhibitor of the Wnt pathway that targets the β-catenin-TCF4 interaction. |
| PC-73060 |
RX-5902
|
RX-5902 (Supinoxin, RX5902) is a small molecule inhibitor of phosphorylated-p68 RNA helicase (P-p68) and attenuates nuclear shuttling of β-catenin. |
| PC-72708 |
ZW4864
|
ZW4864 (ZW-4864) is an orally bioavailable small-molecule that binds with β-catenin and selectively disrupts the PPI between BCL9 and β-catenin, while sparing the β-catenin/E-cadherin PPI. |
| PC-38013 |
Teplinovivint
|
Teplinovivint is a potent Wnt/β-catenin signaling pathway inhibito with anti-inflammatory activity.. |
| PC-35350 |
SKL2001
|
SKL2001 is a specific small molecule activator (agonist) of the Wnt/β-catenin pathway, stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction. |
| PC-35329 |
E-7386
|
E-7386 (E7386) is a potent, orally active modulator of CBP/beta-catenin, disrupts the interaction and inhibits canonical Wnt signaling pathway /TCF reporter gene activity in LiCl-stimulated HEK-293 and MDA-MB-231 with IC50 of 55 and 73 nM, respectively. |
| PC-61323 |
Carnosic acid
|
Carnosic acid (Carnosate) is a naturally occurring phenolic compound with antioxidant, anti-inflammatory and antimicrobial properties, inhibits the BCL9/β-catenin interaction with Ki of 3.3 uM. |
